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Product Info Summary
| SKU: | A09488 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-Placenta-specific protein 1 PLAC1 Antibody
SKU/Catalog Number
A09488
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Placenta-specific protein 1 PLAC1 Antibody (Catalog # A09488). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.
Storage & Handling
PLAC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Placenta-specific protein 1 PLAC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09488)
Host
Rabbit
Contents
PLAC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
PLAC1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human PLAC1. The immunogen is located within amino acids 130 - 180 of PLAC1.
Reactive Species
A09488 is reactive to PLAC1 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
23.6 kDa
Background of PLAC1
PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09488 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PLAC1 antibody can be used for detection of PLAC1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PLAC1 in human placenta tissue lysate with PLAC1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunocytochemistry of PLAC1 in HeLa cells with PLAC1 antibody at 10 μg/mL.
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Immunofluorescence of PLAC1 in Hela cells with PLAC1 antibody at 20 μg/mL.
Specific Publications For Anti-Placenta-specific protein 1 PLAC1 Antibody (A09488)
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