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Product Info Summary
| SKU: | A02817 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-PLCB1 Antibody
View all PLC-beta 1 Antibodies
SKU/Catalog Number
A02817
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PLCB1 Antibody catalog # A02817. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PLCB1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02817)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human EP15R protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02817 is reactive to Plcb1 in Human, Mouse, Rat
Applications
A02817 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
138.396kDa
Background of PLC-beta 1
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth.
Jiang-Hong Man, Nucleic Acids Res., Nov 2006; 34: 5552 - 5566.
Amir Sonnenblick, Mol. Cell. Biol., Dec 2004; 24: 10584 - 10592.
Jianyin Long, PNAS, Jan 2004; 101: 99.
Hyun Duk Jang, J. Biol. Chem., Jun 2004; 279: 24873 - 24880.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For Plcb1 (Source: Uniprot.org, NCBI)
Gene Name
Plcb1
Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
Weight
138.396kDa
Alternative Names
EC 3.1.4.11; EIEE12; FLJ45792; inositoltrisphosphohydrolase; KIAA05811-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1; monophosphatidylinositol phosphodiesterase; phosphoinositidase C; Phosphoinositide phospholipase C-beta-1; phospholipase C, beta 1 (phosphoinositide-specific); Phospholipase C-beta-1; Phospholipase C-I; PI-PLC; PLC-154; PLC154,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1; PLCB1; PLCB1A; PLCB1B; PLCbeta 1; PLC-beta 1; PLC-beta-1; PLC-I; PLC-I1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; triphosphoinositide phosphodiesterase Plcb1|3110043I21Rik, AI132408, Plcb, mKIAA0581|phospholipase C, beta 1|1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1|PLC-154|PLC-beta-1|phosphoinositide phospholipase C|phosphoinositide phospholipase C-beta-1|phospholipase C-beta-1a
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Plcb1, check out the Plcb1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Plcb1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PLCB1 Antibody (A02817)
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No publications found for A02817
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Customer Reviews
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