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Product Info Summary
| SKU: | A08798 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Plxdc2 Antibody
SKU/Catalog Number
A08798
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Plxdc2 Antibody (Catalog # A08798). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Plxdc2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Plxdc2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08798)
Host
Rabbit
Contents
Plxdc2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Plxdc2 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human Plxdc2. The immunogen is located within amino acids 40 - 90 of Plxdc2.
Reactive Species
A08798 is reactive to PLXDC2 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
59.6 kDa
Background of PLXDC2
Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57% amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08798 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Plxdc2 antibody can be used for detection of Plxdc2 by Western blot at 1 and 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human and mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Plxdc2 in human brain tissue lysate with Plxdc2 antibody at (A) 0.5 (B) 1 μg/mL.
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Immunohistochemical staining of human brain tissue using Plxdc2 antibody at 2.5 μg/mL.
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Immunofluorescence of Plxdc2 in Human Brain cells with Plxdc2 antibody at 20 μg/mL.
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Western blot analysis of Plxdc2 in mouse cerebrum tissue lysate with Plxdc2 antibody at (A) 1 and (B) 2 μg/mL.
Specific Publications For Anti-Plxdc2 Antibody (A08798)
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