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Product Info Summary
| SKU: | A08699 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-POLR2B Antibody
SKU/Catalog Number
A08699
Size
100ul
Form
Liquid
Description
Boster Bio Anti-POLR2B Antibody catalog # A08699. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-POLR2B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08699)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from C-terminal of human IFI6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A08699 is reactive to POLR2B in Human, Mouse, Rat
Applications
A08699 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
133.897kDa
Background of RPB2
This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.
Kelly J.M., EMBO J. 5:1601-1606(1986).
Turri M.G., Nucleic Acids Res. 23:1854-1861(1995).
Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-POLR2B Antibody A08699
Western blot analysis of extracts of various cellsProtein Target Info & Infographic
Gene/Protein Information For POLR2B (Source: Uniprot.org, NCBI)
Gene Name
POLR2B
Full Name
DNA-directed RNA polymerase II subunit RPB2
Weight
133.897kDa
Superfamily
RNA polymerase beta chain family
Alternative Names
DNA-directed RNA polymerase II subunit RPB2; EC 2.7.7; EC 2.7.7.6; hRPB140; hsRPB2; POL2RB; polymerase (RNA) II (DNA directed) polypeptide B (140kD); polymerase (RNA) II (DNA directed) polypeptide B, 140kDa; RNA polymerase II subunit 2; RNA polymerase II subunit B2; RNA polymerase II subunit2, RNA polymerase II second largest subunit POLR2B POL2RB, RPB2, hRPB140 RNA polymerase II subunit B DNA-directed RNA polymerase II subunit RPB2|DNA-directed RNA polymerase II 140 kDa polypeptide|DNA-directed RNA polymerase II subunit B|RNA polymerase II second largest subunit|RNA polymerase II subunit 2|RNA polymerase II subunit B2|polymerase (RNA) II (DNA directed) polypeptide B, 140kDa|polymerase (RNA) II subunit B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on POLR2B, check out the POLR2B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for POLR2B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-POLR2B Antibody (A08699)
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No publications found for A08699
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Customer Reviews
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