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Product Info Summary
| SKU: | A12992 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-POLR3C Antibody
SKU/Catalog Number
A12992
Size
100ul
Form
Liquid
Description
Boster Bio Anti-POLR3C Antibody catalog # A12992. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-POLR3C Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12992)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human CENP-M
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A12992 is reactive to POLR3C in Human, Mouse, Rat
Applications
A12992 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
60.612kDa
Background of RPC62
Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene By similarity. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Zhuang D.Z., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Hwang E.S., Immunology 106:464-469(2002).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For POLR3C (Source: Uniprot.org, NCBI)
Gene Name
POLR3C
Full Name
DNA-directed RNA polymerase III subunit RPC3
Weight
60.612kDa
Superfamily
eukaryotic RPC3/POLR3C RNA polymerase subunit family
Alternative Names
DNA-directed III 62 kDa polypeptide; DNA-directed RNA polymerase III subunit C; DNA-directed RNA polymerase III subunit RPC3; polymerase (RNA) III (DNA directed) polypeptide C (62kD); RNA polymerase III 62 kDa subunit; RNA polymerase III subunit C3; RPC62RPC3 POLR3C C82, RPC3, RPC62 RNA polymerase III subunit C DNA-directed RNA polymerase III subunit RPC3|DNA-directed III 62 kDa polypeptide|DNA-directed RNA polymerase III subunit C|RNA polymerase III 62 kDa subunit|RNA polymerase III subunit C3|polymerase (RNA) III (DNA directed) polypeptide C (62kD)|polymerase (RNA) III subunit C
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on POLR3C, check out the POLR3C Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for POLR3C: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-POLR3C Antibody (A12992)
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No publications found for A12992
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