Anti-PPAR Delta Monoclonal Antibody

PPAR delta/NR1C2 antibody

Boster Bio Anti-PPAR Delta Monoclonal Antibody catalog # M01557. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: M01557
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Mouse
Application: IHC

Product Name

Anti-PPAR Delta Monoclonal Antibody

View all PPAR delta/NR1C2 Antibodies

SKU/Catalog Number

M01557

Size

100ul

Form

Liquid

Description

Boster Bio Anti-PPAR Delta Monoclonal Antibody catalog # M01557. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PPAR Delta Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01557)

Host

Mouse

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Monoclonal

Clone Number

2F9

Isotype

IgG

Immunogen

Recombinant peptide derived from PPAR Delta

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M01557 is reactive to PPARD in Human, Mouse, Rat

Applications

M01557 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

49.903kDa

Background of PPAR delta/NR1C2

Bin1 is a conserved member of the BAR family of genes that have been implicated in diverse cellular processes including endocytosis, actin organization, programmed cell death, stress responses, and transcriptional control. The first mammalian BAR protein to be discovered, Amphiphysin I (AmphI), was identified in an immunoscreen for proteins associated with the plasma membranes of synaptic neurons, functions in the control of clathrin-dependent synaptic vesicle endocytosis. The mammalian Bin1 gene was first identified in a two hybrid screen for polypeptides that bind to the N-terminal Myc box 1 (MB1) portion of the c-Myc oncoprotein. Bin1 is similar to AmphI in overall structure, with an N-terminal BAR domain and a C-terminal SH3 domain. However, the Bin1 gene is more complex than the AmphI gene, encoding at least seven different splice variants that differ widely in subcellular localization, tissue distribution, and ascribed functions. Alternate splicing of the Bin1 gene results in ten transcript variants encoding different isoform. Bin1 is expressed ubiquitously in mammalian cells. Certain splice variants of Bin1 are expressed in the neurons, muscle cells or tumor cells. Bin1 may act as a cancer suppressor and inhibits malignant cell transformation. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Bin1 has also been implicated in Alzheimer disease and cardiac disease. Defects in Bin1 are the cause of centronuclear myopathy autosomal recessive; also known as autosomal recessive myotubular myopathy.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC 1:100-200

Validation Images & Assay Conditions

Gene/Protein Information For PPARD (Source: Uniprot.org, NCBI)

Gene Name

PPARD

Full Name

Peroxisome proliferator-activated receptor delta

Weight

49.903kDa

Superfamily

nuclear hormone receptor family

Alternative Names

FAAR; MGC3931; NR1C2; NR1C2PPAR-delta; NUC1; NUC1PPAR-beta; NUCI; NUCII; Nuclear hormone receptor 1; Nuclear receptor subfamily 1 group C member 2; peroxisome proliferative activated receptor, delta; Peroxisome proliferator-activated receptor beta; peroxisome proliferator-activated receptor delta; PPAR delta; PPARB; PPARD PPARD FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB peroxisome proliferator activated receptor delta peroxisome proliferator-activated receptor delta|PPAR-beta|PPAR-delta|PPARD/MYO1D fusion|nuclear hormone receptor 1|nuclear receptor subfamily 1 group C member 2|peroxisome proliferator-activated receptor beta

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PPARD, check out the PPARD Infographic

PPARD infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PPARD: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M01557-100ul

100ul

$380

Free Secondary Antibody

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M01557
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$380.00

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