Anti-PPM1A Picoband™ Antibody

PP2C alpha/PPM1A antibody

Boster Bio Anti-PPM1A Picoband™ Antibody catalog # A02928-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A02928-1
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: ELISA, IHC, WB

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Product Name

Anti-PPM1A Picoband™ Antibody

View all PP2C alpha/PPM1A Antibodies

SKU/Catalog Number

A02928-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-PPM1A Picoband™ Antibody catalog # A02928-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PPM1A Picoband™ Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02928-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence of human PPM1A (HAGSQVAKYCCEHLLDHITNNQDFK).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins.

Reactive Species

A02928-1 is reactive to PPM1A in Human

Applications

A02928-1 is guaranteed for ELISA, IHC, WB Boster Guarantee

Background of PP2C alpha/PPM1A

Protein phosphatase 1A is an enzyme that in humans is encoded by the PPM1A gene. It is mapped to 14q23.1. The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human
Direct ELISA, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For PPM1A (Source: Uniprot.org, NCBI)

Uniprot ID

P35813

Gene ID

5494

Gene Name

PPM1A

Full Name

Protein phosphatase 1A

Weight

42.448kDa

Superfamily

PP2C family

Alternative Names

EC 3.1.3.16; FLJ42306; MGC9201; MMPa-2; MPPa-1; phosphatase 2C alpha; PP2C alpha; Pp2c1; PP2CA; PP2Calpha; PP2C-ALPHA; PPM1A; PPPM1A; protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform; protein phosphatase 1A; protein phosphatase 2C alpha isoform; Protein phosphatase 2C isoform alpha; Protein phosphatase IA; protein phosphatase, Mg2+/Mn2+ dependent, 1A PPM1A PP2C-ALPHA, PP2CA, PP2Calpha protein phosphatase, Mg2+/Mn2+ dependent 1A protein phosphatase 1A

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PPM1A, check out the PPM1A Infographic

PPM1A infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PPM1A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Total: $315

SKU:A02928-1

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A02928-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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