Product Info Summary
SKU: | A02822 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, ICC, WB |
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Product info
Product Name
Anti-PPP2R1A Antibody
SKU/Catalog Number
A02822
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PPP2R1A Antibody catalog # A02822. Tested in WB,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PPP2R1A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02822)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human NRP2 at amino acid range 791-840
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02822 is reactive to PPP2R1A in Human, Mouse, Rat
Applications
A02822 is guaranteed for IF, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
65.309kDa
Background of PPP2R1A
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth.
Jiang-Hong Man, Nucleic Acids Res., Nov 2006; 34: 5552 - 5566.
Amir Sonnenblick, Mol. Cell. Biol., Dec 2004; 24: 10584 - 10592.
Jianyin Long, PNAS, Jan 2004; 101: 99.
Hyun Duk Jang, J. Biol. Chem., Jun 2004; 279: 24873 - 24880.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
ICC/IF: 1:10-1:100
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For PPP2R1A (Source: Uniprot.org, NCBI)
Gene Name
PPP2R1A
Full Name
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
Weight
65.309kDa
Superfamily
phosphatase 2A regulatory subunit A family
Alternative Names
Medium tumor antigen-associated 61 kDa protein; MGC786; PP2A subunit A isoform PR65-alpha; PP2A subunit A isoform R1-alpha; PP2AAALPHA; PP2A-Aalpha; PR65A; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alphaisoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform; protein phosphatase 2, regulatory subunit A, alpha; serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alphaisoform; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alphaisoform PPP2R1A MRD36, PP2A-Aalpha, PP2AA, PP2AAALPHA, PR65A protein phosphatase 2 scaffold subunit Aalpha serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform|medium tumor antigen-associated 61 KDA protein|protein phosphatase 2, regulatory subunit A, alpha|testicular secretory protein Li 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PPP2R1A, check out the PPP2R1A Infographic
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In this infographic, you will see the following information for PPP2R1A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PPP2R1A Antibody (A02822)
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No publications found for A02822
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