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Product Info Summary
| SKU: | A13046 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-Protein SOGA1 SOGA1 Antibody
SKU/Catalog Number
A13046
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Protein SOGA1 SOGA1 Antibody (Catalog # A13046). Tested in ELISA, WB, IF applications. This antibody reacts with Human.
Storage & Handling
SOGA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Protein SOGA1 SOGA1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13046)
Host
Rabbit
Contents
SOGA1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SOGA1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SOGA. The immunogen is located within the last 50 amino acids of SOGA1 .
Cross-reactivity
SOGA1 antibody is human specific. At least four isoforms of SOGA1 are known to exist.
Reactive Species
A13046 is reactive to SOGA1 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
159.8 kDa
Background of SOGA1
The recently identified protein suppressor of glucose by autophagy protein 1 (SOGA1) has been found to be involved in the regulation of autophagy (1). SOGA1 is thought to contribute to adiponectin-mediated insulin-dependent inhibition of autophagy during the activation of adenosine monophosphate kinase (AMPK) (1,2). SOGA1 contains an internal signal peptide that enables the secretion of a circulating fragment of SOGA1, providing a surrogate marker for intracellular SOGA1 levels (2). Knockdown of SOGA1 elevated glucose production in primary hepatocytes indicates that SOGA1 is an inhibitor of glucose production. It thus might be useful as a novel therapeutic target for diabetes (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A13046 is guaranteed for ELISA, IF, WB Boster Guarantee
Recommend Dilution
SOGA1 antibody can be used for detection of SOGA1 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SOGA1 in Hela cell lysate with SOGA1 antibody at (A) 1 and (B) 2 μg/ml.
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Immunofluorescence of SOGA1 in HeLa cells with SOGA1 antibody at 5 μg/mL.
Specific Publications For Anti-Protein SOGA1 SOGA1 Antibody (A13046)
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