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Product Info Summary
| SKU: | A07215 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, ICC, WB |
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Product info
Product Name
Anti-Protein tweety homolog 1 TTYH1 Antibody
SKU/Catalog Number
A07215
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Protein tweety homolog 1 TTYH1 Antibody (Catalog # A07215). Tested in ELISA, WB, ICC applications. This antibody reacts with Human.
Storage & Handling
TTYH1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Protein tweety homolog 1 TTYH1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07215)
Host
Rabbit
Contents
TTYH1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TTYH1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TTYH1. The immunogen is located within the last 50 amino acids of TTYH1.
Cross-reactivity
TTYH1 antibody is human specific. Multiple isoforms of TTYH1 are known to exist.
Reactive Species
A07215 is reactive to TTYH1 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
49.1 kDa
Background of TTYH1
TTYH1 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH1 is a Ca2+-independent, volume-sensitive large conductance chloride (Cl-) channel. TTYH1 is primarily expressed in neural tissue and upregulated in astrocytoma, glioma, and several other cancers. Recent experiments have shown that TTYH1 is an integral endoplasmic reticulum (ER) membrane protein involved in cell proliferation and is thought to play an essential role in embryonic cell growth, possibly through the Ca2+ storage/release process in ER membranes during early development.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07215 is guaranteed for ELISA, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TTYH1 antibody can be used for detection of TTYH1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TTYH1 in Raji cell lysate with TTYH1 antibody at (A) 1 and (B) 2 μg/mL.
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Immunocytochemistry of TTYH1 in Raji cells with TTYH1 antibody at 5 μg/mL.
Specific Publications For Anti-Protein tweety homolog 1 TTYH1 Antibody (A07215)
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