Anti-PSIP1 Antibody

LEDGF antibody

Boster Bio Anti-PSIP1 Antibody catalog # A01960-1. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A01960-1
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

Product Name

Anti-PSIP1 Antibody

View all LEDGF Antibodies

SKU/Catalog Number

A01960-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-PSIP1 Antibody catalog # A01960-1. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PSIP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01960-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human IBP5 protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A01960-1 is reactive to PSIP1 in Human, Mouse, Rat

Applications

A01960-1 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

60.103kDa

Background of LEDGF

Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 5 is a component of E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Cullin 5 seems to be involved proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. Cullin 5 may form a cell surface vasopressin receptor. Cullin 5 is part of a E3 ubiquitin ligase complex with elongin BC complex (TCEB1 and TCEB2), RBX1 and MUF1, complexes with elongin BC complex (TCEB1 and TCEB2), RXB1 and TCEB3 or SOCS1 or WSB1; elongin BC complex (TCEB1 and TCEB2), RBX1 and VHL; elongin BC complex (TCEB1 and TCEB2), RBX1, adenovirus type 5 E1B-55kDa protein and adenovirus type 5 E4-orf6. Cullin 5 Interacts with RBX1 and RNF7.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:50-1:200

Validation Images & Assay Conditions

Gene/Protein Information For PSIP1 (Source: Uniprot.org, NCBI)

Gene Name

PSIP1

Full Name

PC4 and SFRS1-interacting protein

Weight

60.103kDa

Superfamily

HDGF family

Alternative Names

CLL-associated antigen KW-7; Dense fine speckles 70 kDa protein; DFS 70; DFS70; LEDGF; LEDGFDFS 70; Lens epithelium-derived growth factor; MGC74712; p52; p75; PAIP; PC4 and SFRS1 interacting protein 1; PC4 and SFRS1 interacting protein 2; PC4 and SFRS1-interacting protein; PSIP1; PSIP2; transcriptional coactivator p52/p75; Transcriptional coactivator p75/p52 PSIP1 DFS70, LEDGF, PAIP, PSIP2, p52, p75 PC4 and SFRS1 interacting protein 1 PC4 and SFRS1-interacting protein|CLL-associated antigen KW-7|dense fine speckles 70 kDa protein|lens epithelium-derived growth factor|transcriptional coactivator p52/p75

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PSIP1, check out the PSIP1 Infographic

PSIP1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PSIP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01960-1-100ul

100ul

$405

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A01960-1
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