Anti-RAC1 Antibody

Rac1 antibody

Anti-RAC1 Antibody

Product Info Summary

SKU: M00041-1
Size: 80 ul
Reactive Species: Human, Rat
Host: Mouse
Application: Flow Cytometry, IHC-P, WB

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Product Name

Anti-RAC1 Antibody

View all Rac1 Antibodies

SKU/Catalog Number

M00041-1

Size

80 ul

Description

Anti-RAC1 Antibody

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-RAC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00041-1)

Host

Mouse

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Clonality

Monoclonal

Isotype

IgG2b

Immunogen

This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from human.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00041-1 is reactive to RAC1 in Human, Rat

Applications

M00041-1 is guaranteed for Flow Cytometry, IHC-P, WB Boster Guarantee

Background of Rac1

Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Stimulates PKN2 kinase activity. In concert with RAB7A, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts. In glioma cells, promotes cell migration and invasion. In podocytes, promotes nuclear shuttling of NR3C2; this modulation is required for a proper kidney functioning. Required for atypical chemokine receptor ACKR2-induced LIMK1-PAK1-dependent phosphorylation of cofilin (CFL1) and for up-regulation of ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. In synapses, seems to mediate the regulation of F-actin cluster formation performed by SHANK3.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Validation Images & Assay Conditions

Gene/Protein Information For RAC1 (Source: Uniprot.org, NCBI)

Uniprot ID

P63000

Gene ID

5879

Gene Name

RAC1

Full Name

Ras-related C3 botulinum toxin substrate 1

Weight

21.45kDa

Superfamily

small GTPase superfamily

Alternative Names

Cell migration-inducing gene 5 protein; MGC111543; p21-Rac1; p21-Rac1migration-inducing gene 5; Rac1; Ras-like protein TC25; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP bindingprotein Rac1); ras-related C3 botulinum toxin substrate 1; rho family, small GTP binding protein Rac1; TC25; TC-25 RAC1 MIG5, MRD48, Rac-1, TC-25, p21-Rac1 Rac family small GTPase 1 ras-related C3 botulinum toxin substrate 1|cell migration-inducing gene 5 protein|ras-like protein TC25|ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on RAC1, check out the RAC1 Infographic

RAC1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for RAC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Size

Total: $170

SKU:M00041-1

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Ships directly to USA and Canada. For other regions, visit our distributors page

Bulk Inquiry

In stock
Order Product
M00041-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$170.00

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