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Product Info Summary
| SKU: | A04117 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-Ras-related protein R-Ras2 RRAS2 Antibody
SKU/Catalog Number
A04117
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Ras-related protein R-Ras2 RRAS2 Antibody (Catalog # A04117). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
RRAS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Ras-related protein R-Ras2 RRAS2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04117)
Host
Rabbit
Contents
RRAS2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal RRAS2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human RRAS2. The immunogen is located within the last 50 amino acids of RRAS2.
Cross-reactivity
Two isoforms of RRAS2 exists as a result of alternative splicing event.
Reactive Species
A04117 is reactive to RRAS2 in Human, Mouse
Observed Molecular Weight
68 kDa
Calculated molecular weight
23.4 kDa
Background of RRAS2
Activating mutations and overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55–60%. RRAS2 is a small GTPbinding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04117 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
RRAS2 antibody can be used for detection of RRAS2 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of RRAS2 in Jurkat cell lysate with RRAS2 antibody at (A) 1 and (B) 2 μg/mL
Specific Publications For Anti-Ras-related protein R-Ras2 RRAS2 Antibody (A04117)
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