Rabbit IgG polyclonal antibody for Resistin(RETN) detection. Tested with WB, IHC-P in Mouse.
Anti-Resistin/RETN Antibody Info At A Glance
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|Product Name||Anti-Resistin/RETN Antibody
See all Resistin primary antibodies, ELISA kits and proteins
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Polyclonal antibody for Resistin/RETN detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Mouse. Resistin/RETN information: Molecular Weight: 12492 MW; Subcellular Localization: Secreted; Tissue Specificity: Expressed in white but not brown adipose tissue in a variety of organs.|
|Cite This Product||Anti-Resistin/RETN Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1473)|
|Similar Products From
|Anti-Resistin/RETN Antibody may replace the following items: sc 160690.|
*Our Boster Guarantee covers the use of this product in the above tested applications.
*Innovating Scientists reward: if you test this antibody on a species or application not listed above and share with us your results, we will provide you a full credit to purchase Boster products.
|Related Products||Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
*Blocking peptide can be purchased at $50. Contact us for more information.
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion all year round.
|Immunogen||A synthetic peptide corresponding to a sequence at the C-terminus of mouse Resistin(93-114aa CHCQCARIDWTAARCCKLQVAS).|
|Cross Reactivity||No cross reactivity with other proteins|
Gene/Protein Basic Information For Retn (Source: Uniprot.org, NCBI)
|NCBI Gene Id||57264|
|Species Of This Entry||Mouse|
|Alternative Names||Resistin|Adipose tissue-specific secretory factor; ADSF; ADSFMGC126609; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich proteinprecursor 1; C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like 2; Cysteine-rich secreted protein FIZZ3; FIZZ3; FIZZ3MGC126603; found in inflammatory zone 3; HXCP1; Resistin; RETN; RETN1; RSTNXCP1|
|Post Tranlational Modifications||Phosphorylation; Oxidation; Glycosylation; Reduction; Cleavage; Acetylation; Dephosphorylation; Acylation|
|Gene Location||8 A1.1|8 1.92 cM, on Chromasome 8, gene sequence:|
*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
Ontology For Retn (Source: Uniprot.org, NCBI)
|Protein Function||Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes.|
|Tissue Specificity||Expressed in white but not brown adipose tissue in a variety of organs.|
|Related Diseases||Insulin Resistance; Obesity; Diabetes Mellitus; Diabetes Mellitus, Non-insulin-dependent; Insulin Sensitivity; Inflammation; Cardiovascular Diseases; Atherosclerosis; Impaired Glucose Tolerance; Metabolic Syndrome X; Hypertensive Disease; Hyperinsulinism; Malignant Neoplasms; Polycystic Ovary Syndrome; Hyperglycemia; Dyslipidemias; Tissue Adhesions; Coronary Artery Disease; Metabolic Diseases|
|Related Pathways||Secretion; Pathogenesis; Glucose Homeostasis; Energy Homeostasis; Cell Adhesion; Transport; Lipid Homeostasis; Protein Secretion; Inflammatory Response; Insulin Secretion; Menopause; Glomerular Filtration; Cell Activation; Cell Differentiation; Cell Proliferation; Endothelial Cell Activation; Reverse Transcription; Glucose Transport; Localization; Lipid Oxidation|
|Background||Resistin, also known as adipose tissue-specific secretory factor(ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein(XCP1) is a cysteine-rich protein that in humans is encoded by the RETN gene. The resistin gene comprises 4 exons, the first of which is untranslated, and spans approximately 1,750 bp. The human resistin gene is localized to a cloned fragment of human chromosome 19. In primates, pigs and dogs, resistin is secreted by immune and epithelial cells while in rodents, it is secreted by adipose tissue. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus.|
|Scientific References||PMID: 11201732 by Steppan C.M., et al. The hormone resistin links obesity to diabetes.|
PMID: 11358969 by Banerjee R.R., et al. Dimerization of resistin and resistin-like molecules is determined by a single cysteine.
Our Boster Quality Guarantee for Anti-Resistin/RETN Antibody covers its use in the following applications.Immunohistochemistry(Paraffin-embedded Section), 0.5-1μg/ml, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Mouse
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
Lane 1: Recombinant Mouse Resistin Protein 10ng
Lane 2: Recombinant Mouse Resistin Protein 5ng
Boster provides comprehensive technical information for WB, IHC/IF/ICC, Flow Cytometry sample preparation protocols, assay protocols, troubleshooting tips and assay optimization tips.
- Western Blottting Resource Center
- Immunohistochemistry Resource Center
- Flow Cytometry Technical Resource Center
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Note: sample size takes longer to process, average 5-7 days.
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