Product Info Summary
SKU: | A02625 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-Retinal guanylyl cyclase 1 GUCY2D Antibody
SKU/Catalog Number
A02625
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Retinal guanylyl cyclase 1 GUCY2D Antibody catalog # A02625. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Retinal guanylyl cyclase 1 GUCY2D Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02625)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human PBK around the phosphorylation site of T9.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02625 is reactive to GUCY2D in Human, Mouse, Rat
Applications
A02625 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
120.059kDa
Background of GUCY2D
p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.
Tsai L.-H., Nature 371:419-423(1994).
Patrick G.N., Nature 402:615-622(1999).
Kesavapany S., J. Neurosci. 24:4421-4431(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:200-1:2000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-Retinal guanylyl cyclase 1 GUCY2D Antibody A02625
Western blot analysis of extracts of various cellsProtein Target Info & Infographic
Gene/Protein Information For GUCY2D (Source: Uniprot.org, NCBI)
Gene Name
GUCY2D
Full Name
Retinal guanylyl cyclase 1
Weight
120.059kDa
Superfamily
adenylyl cyclase class-4/guanylyl cyclase family
Alternative Names
CORD6cone rod dystrophy 5/6; CYGD; EC 4.6.1; guanylate cyclase 2D, membrane (retina-specific); Guanylate cyclase 2D, retinal; GUC1A4; GUC2DCORD5; LCA; LCA1RCD2; retGC; RETGC1; RETGC-1EC 4.6.1.2; retinal guanylyl cyclase 1; Rod outer segment membrane guanylate cyclase; ROSGC; ROS-GC; ROS-GC1 GUCY2D CACD1, CG-E, CORD5, CORD6, CSNB1I, CYGD, GUC1A4, GUC2D, LCA, LCA1, RCD2, RETGC-1, ROS-GC1, ROSGC, retGC guanylate cyclase 2D, retinal retinal guanylyl cyclase 1|ROS-GC|cone rod dystrophy 6|guanylate cyclase 2D, membrane (retina-specific)|retinal guanylate cyclase 1|rod outer segment membrane guanylate cyclase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GUCY2D, check out the GUCY2D Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GUCY2D: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Retinal guanylyl cyclase 1 GUCY2D Antibody (A02625)
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No publications found for A02625
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