Anti-RGMC HFE2 Antibody

Product Name

Anti-RGMC HFE2 Antibody

View all Hjv Antibodies

SKU/Catalog Number

A02119

Size

100 ul

Form

Liquid

Description

Boster Bio Anti-RGMC HFE2 Antibody catalog # A02119. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-RGMC HFE2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02119)

Host

Rabbit

Contents

Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human RGMC protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02119 is reactive to Hjv in Human, Mouse, Rat

Applications

A02119 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

44.848kDa

Background of Hjv

Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) By similarity. Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

Hateboer G., EMBO J. 14:3159-3169(1995).
Deloukas P., Nature 429:375-381(2004).
Matsuoka S., Science 316:1160-1166(2007).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-2000
ELISA 1:5000-20000

Validation Images & Assay Conditions

Click image to see more details

Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°C over night

Gene/Protein Information For Hjv (Source: Uniprot.org, NCBI)

Alternative Names

Hemojuvelin Hjv|2310035L15Rik, 5230400G09Rik, AI414844, AI789733, DL-, DL-M, HJ, Hfe2, Rgm, Rgmc, hemoju, hemojuvelin|hemojuvelin BMP co-receptor|hemojuvelin|RGM domain family member C|hemochromatosis type 2 (juvenile) (human homolog)|hemochromatosis type 2 protein homolog|hemojuvelin BMP coreceptor|repulsive guidance molecule C

For more info on Hjv, check out the Hjv Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Hjv: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Take me to the Hjv Infographic

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis