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Product Info Summary
| SKU: | A09915 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IHC-P |
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Product info
Product Name
Anti-RIM2 RIMS2 Antibody
SKU/Catalog Number
A09915
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-RIM2 RIMS2 Antibody (Catalog # A09915). Tested in ELISA, IHC-P applications. This antibody reacts with Human.
Storage & Handling
RIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-RIM2 RIMS2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09915)
Host
Rabbit
Contents
RIM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
RIM2 antibody was raised against a 16 amino acid peptide near the carboxy terminusof human RIM2. The immunogen is located within amino acids 30 - 80 of RIM2.
Reactive Species
A09915 is reactive to RIMS2 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
160.4 kDa
Background of RIMS2
Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. RIM1 and RIM2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release; synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like RIM1, RIM2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09915 is guaranteed for ELISA, IHC-P Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
RIM2 antibody can be used for detection of RIM2 by immunohistochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Immunohistochemistry of RIM2 in human adrenal gland tissue with RIM2 antibody at 5 μg/mL.
Specific Publications For Anti-RIM2 RIMS2 Antibody (A09915)
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