Anti-RIPK3 Antibody

RIPK3/RIP3 antibody

Anti-RIPK3 Antibody

Product Info Summary

SKU: M00202
Size: 50 ul
Reactive Species: Human
Host: Mouse
Application: WB

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Product Name

Anti-RIPK3 Antibody

View all RIPK3/RIP3 Antibodies

SKU/Catalog Number

M00202

Size

50 ul

Description

Purified Mouse Monoclonal Antibody (Mab)

Storage & Handling

Cite This Product

Anti-RIPK3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00202)

Host

Mouse

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Clonality

Monoclonal

Isotype

IgG1,κ

Immunogen

This RIPK3 antibody is generated from a mouse immunized with a recombinate protein from the human region of human RIPK3.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00202 is reactive to RIPK3 in Human

Applications

M00202 is guaranteed for WB Boster Guarantee

Background of RIPK3/RIP3

Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Validation Images & Assay Conditions

Gene/Protein Information For RIPK3 (Source: Uniprot.org, NCBI)

Uniprot ID

Q9Y572

Gene ID

11035

Gene Name

RIPK3

Full Name

Receptor-interacting serine/threonine-protein kinase 3

Weight

56.887kDa

Superfamily

protein kinase superfamily

Alternative Names

EC 2.7.11.1; Receptor-interacting protein 3; receptor-interacting serine/threonine-protein kinase 3; receptor-interacting serine-threonine kinase 3; RIP3; RIP-3; RIP3receptor interacting protein 3; RIPK3; RIP-like protein kinase 3 RIPK3 RIP3 receptor interacting serine/threonine kinase 3 receptor-interacting serine/threonine-protein kinase 3|RIP-3|RIP-like protein kinase 3|receptor interacting protein 3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on RIPK3, check out the RIPK3 Infographic

RIPK3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for RIPK3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Size

Total: $170

SKU:M00202

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Ships directly to USA and Canada. For other regions, visit our distributors page

Bulk Inquiry

In stock
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M00202
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$170.00

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