RIPK3 Antibodies

AND RIPK3 ELISA kits, RIPK3 Proteins

Many biological assays use antibodies to detect RIPK3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RIPK3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RIPK3 antibodies...

We validate the specificity of these antibodies to RIPK3 by testing them on tissues known to express RIPK3 positively and negatively. Browse below to find the RIPK3 antibody that suites your experiment. We have 9 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RIPK3 Infographic by Boster Bio

All RIPK3 Products

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Applications

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Anti-RIP3/RIPK3 Antibody Picoband®

3 Citations 4 Q&As

Anti-RIP3 antibody, PA2242, Western blottingLane 1: PANC Cell LysateLane 2: SW620 Cell LysateLane 3: SKOV-3 Cell LysateLane 4: M231 Cell Lysate

Conditional knockout of TGF-βRII prevented cisplatin-induced renal injury and apoptotic signaling in vivo

Conditional knockout of Smad2 prevented cisplatin-induced renal injury, decline of renal function and attenuated signaling molecules regulating programmed cell death in vivo

Human

$370
Cat # PA2242
100 μg/vial

Anti-RIPK3 Antibody

Human

$299
Cat # M00202
50 µl

Anti-RIP3 (RIPK3) Mouse Monoclonal Antibody [Clone ID: OTI1B3]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RIPK3 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (10ug) from 2 different cell lines by using anti-RIPK3 monoclonal antibody at 1:200

Human

IHC, WB

$523
Cat # M00202-1
100 µl

Anti-Phospho-RIP3 (S232) Rabbit Monoclonal Antibody

Western blot analysis of Phospho-RIP3 (S232) using anti-Phospho-RIP3 (S232) antibody (M00202S232)

Mouse, Rat

$370
Cat # M00202S232
100 µl/vial

Anti-RIP3 Rabbit Monoclonal Antibody

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-RIP3 antibody

Mouse

ELISA, IP, IF, WB

$146
Cat # M00202-2
20μL, 40μL, 100μL, 200μL

Anti-RIP3/RIPK3 (Phospho-S232) Antibody (Monoclonal, 35R03)

Western blot analysis of RIP3/RIPK3 using anti-RIP3/RIPK3 antibody (M00202-3)

Mouse, Rat

IF, ICC, WB

$370
Cat # M00202-3
100 μl/vial

Anti-Phospho-RIP3/RIPK3 (S199) Antibody

Human, Rat

IF, IHC, ICC

$370
Cat # P00202
100 μl/vial

Anti-Phospho-RIP3/RIPK3 (T231/S232) Antibody

Mouse, Rat

ELISA

$370
Cat # P00202-1
100 μl/vial

Anti-Phospho-RIP3/RIPK3 (S316) Antibody

Human

$370
Cat # P00202-2
100 μl/vial

RIPK3 Overview

Facts about Receptor-interacting serine/threonine-protein kinase 3.

RIPK3 3D structure. Source: alphafold

Receptor-interacting serine/threonine-protein kinase 3 (RIPK3)

Critical for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complicated.

RIPK3 binds to and enhances the action of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes can eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.

Gene Information

Human
Gene Name:	RIPK3
Uniprot:	Q9Y572
Entrez:	11035

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.11.1; Receptor-interacting protein 3; receptor-interacting serine/threonine-protein kinase 3; receptor-interacting serine-threonine kinase 3; RIP3; RIP-3; RIP3receptor interacting protein 3; RIPK3; RIP-like protein kinase 3

Molecular Weight

Mass (kDA):
56.887 kDA

Genomic Context


Human

Location:	14q12
Sequence:	14; NC_000014.9 (24336025..24339991, complement)

Tissue Specificity

Highly expressed in the pancreas. Detected at lower levels in heart, placenta, lung and kidney. Isoform 3 is significantly increased in colon and lung cancers.