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Product Info Summary
| SKU: | A09281 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-Rkhd2 MEX3C Antibody
SKU/Catalog Number
A09281
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Rkhd2 MEX3C Antibody (Catalog # A09281). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Rkhd2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Rkhd2 MEX3C Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09281)
Host
Rabbit
Contents
Rkhd2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rkhd2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RKHD2. The immunogen is located within amino acids 540 - 590 of Rkhd2.
Reactive Species
A09281 is reactive to MEX3C in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
69.4 kDa
Background of MEX3C
Rkhd2, also known as MEX3C is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd2, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. It has been suggested that genetic variations in Rkhd2 may be associated with susceptibility to essential hypertension type 8. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09281 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Rkhd2 antibody can be used for detection of Rkhd2 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Rkhd2 in rat heart tissue lysate with Rkhd2 antibody at (A) 0.5 μg/mL and (B) 1 μg/mL.
Specific Publications For Anti-Rkhd2 MEX3C Antibody (A09281)
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