Anti-RXRB Antibody

RXR beta/NR2B2 antibody

Boster Bio Anti-RXRB Antibody catalog # A05488. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A05488
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, WB

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Product Name

Anti-RXRB Antibody

View all RXR beta/NR2B2 Antibodies

SKU/Catalog Number

A05488

Size

100ul

Form

Liquid

Description

Boster Bio Anti-RXRB Antibody catalog # A05488. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-RXRB Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05488)

Host

Rabbit

Contents

Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human RXRB protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05488 is reactive to RXRB in Human, Mouse, Rat

Applications

A05488 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

111 kDa

Calculated molecular weight

56.922kDa

Background of RXR beta/NR2B2

Isoform GANP:Essential for the generation of high-affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation-dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells By similarity. Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Isoform MCM3AP:Acetyltransferase targeting MCM3. Inhibits initiation of DNA replication, but not elongation.

Nobuo Sakaguchi, J. Immunol., Apr 2005; 174: 4485 - 4494.
Kazuhiko Kuwahara, Blood, Apr 2000; 95: 2321 - 2328.
Y Kono, K Maeda, Genes Cells, Aug 2002; 7: 821 - 834.
Kazuhiko Kuwahara, PNAS, Aug 2001; 98: 10279.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-2000 ELISA 1:5000-20000

Validation Images & Assay Conditions

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Gene/Protein Information For RXRB (Source: Uniprot.org, NCBI)

Gene Name

RXRB

Full Name

Retinoic acid receptor RXR-beta

Weight

56.922kDa

Superfamily

nuclear hormone receptor family

Alternative Names

DAUDI6; H-2RIIBP; MHC class I promoter binding protein; NR2B2; NR2B2MGC1831; Nuclear receptor subfamily 2 group B member 2; RCoR-1; retinoic acid receptor RXR-beta; Retinoid X receptor beta; retinoid X receptor, beta; RXR beta; RXRB RXRB DAUDI6, H-2RIIBP, NR2B2, RCoR-1 retinoid X receptor beta retinoic acid receptor RXR-beta|MHC class I promoter binding protein|nuclear receptor subfamily 2 group B member 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on RXRB, check out the RXRB Infographic

RXRB infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for RXRB: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A05488-100ul

100ul

$380

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A05488
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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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