Anti-SELK SELENOK Antibody

SELENOK antibody

Boster Bio Anti-SELK SELENOK Antibody (Catalog # A31964). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A31964
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, WB

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Product Name

Anti-SELK SELENOK Antibody

View all SELENOK Antibodies

SKU/Catalog Number

A31964

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-SELK SELENOK Antibody (Catalog # A31964). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

SELK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-SELK SELENOK Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A31964)

Host

Rabbit

Contents

SELK Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

Clone: SK7

Isotype

IgG

Immunogen

SELK antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SELK. The immunogen is located within the last 50 amino acids of SELK.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

It is predicted to not cross-react with other members of the cavin family.

Reactive Species

A31964 is reactive to SELENOK in Human, Mouse, Rat

Applications

A31964 is guaranteed for ELISA, IF, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

10.645kDa

Background of SELENOK

SELK is a selenoprotein, containing a selenocysteine residue at its active site. SELK is localized to the endoplasmic reticulum and is highly expressed in the heart, where it may function as an antioxidant. SELK can bind to proteins such as the ER-associated degradation (ERAD) components p97 ATPase, Derlin-1 and -2, and SelS as well as proteins in the oligosaccharyltransferase complex, suggesting that SELK may be involved in the Derlin-dependent ERAD of glycosylated misfolded proteins. SELK is also thought to be important in Ca2+ flux in immune cells, and is cleaved by m-calpain in resting macrophages. When these macrophages are activated through different Toll-like receptors, this cleavage is inhibited

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

SELK antibody can be used for detection of SELK by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For SELENOK (Source: Uniprot.org, NCBI)

Gene Name

SELENOK

Full Name

Selenoprotein K

Weight

10.645kDa

Superfamily

selenoprotein K family

Alternative Names

Selenoprotein K SELENOK HSPC030, HSPC297, SELK selenoprotein K selenoprotein K

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SELENOK, check out the SELENOK Infographic

SELENOK infographic

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In this infographic, you will see the following information for SELENOK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A31964-0.1 mg

0.1 mg

$449

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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