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- Table of Contents
Facts about Selenoprotein K.
Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low- density lipoprotein and in foam cell formation (By similarity). Together with ZDHHC6, required for palmitoylation of ITPR1 in immune cells, leading to regulate ITPR1 stability and function (PubMed:25368151).
| Human | |
|---|---|
| Gene Name: | SELENOK |
| Uniprot: | Q9Y6D0 |
| Entrez: | 58515 |

| Belongs to: |
|---|
| selenoprotein K family |

Selenoprotein K
Mass (kDA):
10.645 kDA

| Human | |
|---|---|
| Location: | 3p21.1 |
| Sequence: | 3; NC_000003.12 (53884417..53891859, complement) |
Highly expressed in heart.
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein. Probably mainly localized in the ER.


PMID: 12775843 by Kryukov G.V., et al. Characterization of mammalian selenoproteomes.
PMID: 16962588 by Lu C., et al. Identification and characterization of selenoprotein K: an antioxidant in cardiomyocytes.