Product Info Summary
SKU: | M00720-1 |
---|---|
Size: | 100 μl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IP, IF, IHC, ICC, WB |
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Product info
Product Name
Anti-SERPINA1/Alpha 1 Antitrypsin Rabbit Monoclonal Antibody
View all Serpin A1/alpha 1-Antitrypsin Antibodies
SKU/Catalog Number
M00720-1
Size
100 μl
Form
Liquid
Description
Boster Bio Anti-SERPINA1/Alpha 1 Antitrypsin Rabbit Monoclonal Antibody catalog # M00720-1. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-SERPINA1/Alpha 1 Antitrypsin Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00720-1)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clonality
Monoclonal
Clone Number
AOEF-19
Isotype
Rabbit IgG
Immunogen
A synthesized peptide derived from human SERPINA1
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00720-1 is reactive to SERPINA1 in Human
Applications
M00720-1 is guaranteed for IP, IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
37 kDa
Calculated molecular weight
46.737kDa
Background of Serpin A1/alpha 1-Antitrypsin
Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:30
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of SERPINA1 expression in human fetal kidney lysate.
Protein Target Info & Infographic
Gene/Protein Information For SERPINA1 (Source: Uniprot.org, NCBI)
Gene Name
SERPINA1
Full Name
Alpha-1-antitrypsin
Weight
46.737kDa
Superfamily
serpin family
Alternative Names
A1A; A1AT; AATMGC23330; alpha 1-Antitrypsin; alpha 1-Proteinase Inhibitor; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; alpha-1-antitrypsin; antitrypsin), member 1; member 1; PIMGC9222; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase; serine (or cysteine) proteinase inhibitor, clade A, member 1; Serpin A1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin) SERPINA1 A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT, nNIF serpin family A member 1 alpha-1-antitrypsin|alpha-1 antitrypsin|alpha-1 protease inhibitor|alpha-1-antiproteinase|alpha-1-antitrypsin short transcript variant 1C4|alpha-1-antitrypsin short transcript variant 1C5|epididymis secretory sperm binding protein|protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin|serine (or cysteine) proteinase inhibitor, clade A, member 1|serpin A1|serpin peptidase inhibitor clade A (alpha-1antiproteinase, antitrypsin) member 1|serpin peptidase inhibitor clade A member 1|serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SERPINA1, check out the SERPINA1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SERPINA1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SERPINA1/Alpha 1 Antitrypsin Rabbit Monoclonal Antibody (M00720-1)
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No publications found for M00720-1
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Customer Reviews
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Customer Q&As
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1 Customer Q&As for Anti-SERPINA1/Alpha 1 Antitrypsin Rabbit Monoclonal Antibody
Question
Has M00720-1 been tested for cross-reactivity with cynomolgus monkey A1AT?
Verified customer
Asked: 2019-11-14
Answer
No test/s was done with samples from cynomolgus monkey using the Anti-SERPINA1/Alpha 1 Antitrypsin Rabbit Monoclonal Antibody (M00720-1). The immunogen of it is native protein. It is not certain if it would cross react with cynomolgus monkey.
Boster Scientific Support
Answered: 2019-11-15