Anti-Protein C inhibitor/SERPINA5 Antibody Picoband™

Serpin A5/Protein C Inhibitor antibody

Boster Bio Anti-Protein C inhibitor/SERPINA5 Antibody Picoband™ catalog # A01916-1. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A01916-1
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

Product Name

Anti-Protein C inhibitor/SERPINA5 Antibody Picoband™

View all Serpin A5/Protein C Inhibitor Antibodies

SKU/Catalog Number

A01916-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Protein C inhibitor/SERPINA5 Antibody Picoband™ catalog # A01916-1. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Protein C inhibitor/SERPINA5 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01916-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human SERPINA5 recombinant protein (Position: S86-P406). Human SERPINA5 shares 66% amino acid (aa) sequence identity with mouse SERPINA5.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

A01916-1 is reactive to SERPINA5 in Human, Mouse, Rat

Applications

A01916-1 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

46 kDa

Calculated molecular weight

45.675kDa

Background of Serpin A5/Protein C Inhibitor

Protein C inhibitor (PCI), also known as SERPINA5, is serine protease inhibitor of serpin type that is found in most tissues and fluids, including blood plasma, seminal plasma and urine of human. It is a 52kD glycoprotein and belongs to serine protease inhibitor (Serpin) super family of protein. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs. This gene is mapped on the q arm of chromosome 14.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human, Rat

Validation Images & Assay Conditions

Gene/Protein Information For SERPINA5 (Source: Uniprot.org, NCBI)

Gene Name

SERPINA5

Full Name

Plasma serine protease inhibitor

Weight

45.675kDa

Superfamily

serpin family

Alternative Names

Acrosomal serine protease inhibitor; antitrypsin), member 5; member 5; PAI-3; PAI3PLANH3; PCI; PCIplasminogen activator inhibitor III; Plasminogen activator inhibitor 3; plasminogen activator inhibitor-3; PROCIplasma serine protease inhibitor; Protein C inhibitor; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase; Serpin A5; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin); SERPNA5 SERPINA5 PAI-3, PAI3, PCI, PCI-B, PLANH3, PROCI serpin family A member 5 plasma serine protease inhibitor|acrosomal serine protease inhibitor|plasminogen activator inhibitor III|plasminogen activator inhibitor-3|protein C inhibitor|serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5|serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SERPINA5, check out the SERPINA5 Infographic

SERPINA5 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SERPINA5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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3 Customer Q&As for Anti-Protein C inhibitor/SERPINA5 Antibody Picoband™

Question

My question regarding product A01916-1, anti-Protein C inhibitor/SERPINA5 antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?

B. Moore

Verified customer

Asked: 2019-10-29

Answer

We do not advise storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free A01916-1 anti-Protein C inhibitor/SERPINA5 antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.

Boster Scientific Support

Answered: 2019-10-29

Question

We are currently using anti-Protein C inhibitor/SERPINA5 antibody A01916-1 for mouse tissue, and we are happy with the IHC results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on feline tissues as well?

K. Jha

Verified customer

Asked: 2018-11-02

Answer

The anti-Protein C inhibitor/SERPINA5 antibody (A01916-1) has not been tested for cross reactivity specifically with feline tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2018-11-02

Question

Would anti-Protein C inhibitor/SERPINA5 antibody A01916-1 work on canine WB with testis?

Verified Customer

Verified customer

Asked: 2017-10-16

Answer

Our lab technicians have not validated anti-Protein C inhibitor/SERPINA5 antibody A01916-1 on canine. You can run a BLAST between canine and the immunogen sequence of anti-Protein C inhibitor/SERPINA5 antibody A01916-1 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated canine samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in canine testis in WB, you can get your next antibody for free.

Boster Scientific Support

Answered: 2017-10-16

Order DetailsPrice
A01916-1

100μg

$370
A01916-1-10ug

10μg sample (liquid)

$99
A01916-1-Biotin

100 μg Biotin conjugated

$570
A01916-1-Cy3

100 μg Cy3 conjugated

$570
A01916-1-Dylight488

100 μg Dylight488 conjugated

$570
A01916-1-Dylight550

100 μg Dylight550 conjugated

$570
A01916-1-Dylight594

100 μg Dylight594 conjugated

$570
A01916-1-FITC

100 μg FITC conjugated

$570
A01916-1-HRP

100 μg HRP conjugated

$570
A01916-1-APC

100 μg APC conjugated

$670
A01916-1-PE

100 μg PE conjugated

$670
A01916-1-carrier-free

Carrier Free

$370

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A01916-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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