Anti-SGOL2 Antibody (Center)

SGO2 antibody

Boster Bio Anti-SGOL2 Antibody (Center) (Catalog # A30763-1). Tested in WB application(s). This antibody reacts with Human.

Product Info Summary

SKU: A30763-1
Size: 80 µl
Reactive Species: Human
Host: Rabbit
Application: WB

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Product Name

Anti-SGOL2 Antibody (Center)

View all SGO2 Antibodies

SKU/Catalog Number

A30763-1

Size

80 µl

Description

Boster Bio Anti-SGOL2 Antibody (Center) (Catalog # A30763-1). Tested in WB application(s). This antibody reacts with Human.

Storage & Handling

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Cite This Product

Anti-SGOL2 Antibody (Center) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A30763-1)

Host

Rabbit

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

This SGOL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the Central region of human SGOL2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A30763-1 is reactive to SGO2 in Human

Reconstitution

Calculated molecular weight

144739 Da

Background of SGO2

Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A30763-1 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:1000

Validation Images & Assay Conditions

Gene/Protein Information For SGO2 (Source: Uniprot.org, NCBI)

Gene Name

SGO2

Full Name

Shugoshin 2

Weight

144739 Da

Superfamily

shugoshin family

Alternative Names

Shugoshin-like 2, Shugoshin-2, Sgo2, Tripin, SGOL2 SGO2 SGOL2, TRIPIN shugoshin 2 shugoshin 2|shugoshin-like 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SGO2, check out the SGO2 Infographic

SGO2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SGO2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A30763-1-80ul

80 μl

$299
A30763-1-400ul

400 μl

$347

Free Secondary Antibody

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A30763-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$299.00

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