Anti-SHANK3 Antibody Picoband™

Shank3 antibody

Boster Bio Anti-SHANK3 Antibody Picoband™ catalog # A01231-1. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A01231-1
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, Flow Cytometry, IHC, WB

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Product Name

Anti-SHANK3 Antibody Picoband™

View all Shank3 Antibodies

SKU/Catalog Number

A01231-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-SHANK3 Antibody Picoband™ catalog # A01231-1. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SHANK3 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01231-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human SHANK3 recombinant protein (Position: E1391-H1698).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01231-1 is reactive to Shank3 in Human, Mouse, Rat

Applications

A01231-1 is guaranteed for ELISA, Flow Cytometry, IHC, WB Boster Guarantee

Observed Molecular Weight

180-190 kDa

Calculated molecular weight

185.397kDa

Background of Shank3

SH3 and multiple ankyrin repeat domains 3 (Shank3), also known as proline-rich synapse-associated protein 2 (ProSAP2), is a protein that in humans is encoded by the SHANK3 gene. This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Additionally, Shank proteins play a role in synapse formation and dendritic spine maturation. Mutations in this gene are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in this gene also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for this gene but they have not yet been experimentally verified.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.25μg/ml, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human, Rat
Flow Cytometry, 1-3μg/1x106 cells, Human, Mouse, Rat
Direct ELISA, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For Shank3 (Source: Uniprot.org, NCBI)

Gene Name

Shank3

Full Name

SH3 and multiple ankyrin repeat domains protein 3

Weight

185.397kDa

Superfamily

SHANK family

Alternative Names

DEL22q13.3; KIAA1650proline rich synapse associated protein 2; Proline-rich synapse-associated protein 2; prosap2; PSAP2SH3 and multiple ankyrin repeat domains protein 3; SH3 and multiple ankyrin repeat domains 3; shank postsynaptic density protein; Shank3; SPANK-2 Shank3|AI841104, P, Spank-2, proSAP2|SH3 and multiple ankyrin repeat domains 3|SH3 and multiple ankyrin repeat domains protein 3|SH3/ankyrin domain gene 3|proline-rich synapse-associated protein 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Shank3, check out the Shank3 Infographic

Shank3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Shank3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01231-1

100μg

$370
A01231-1-10ug

10μg sample (liquid)

$99
A01231-1-Biotin

100 μg Biotin conjugated

$570
A01231-1-Cy3

100 μg Cy3 conjugated

$570
A01231-1-Dylight488

100 μg Dylight488 conjugated

$570
A01231-1-Dylight550

100 μg Dylight550 conjugated

$570
A01231-1-Dylight594

100 μg Dylight594 conjugated

$570
A01231-1-FITC

100 μg FITC conjugated

$570
A01231-1-HRP

100 μg HRP conjugated

$570
A01231-1-APC

100 μg APC conjugated

$670
A01231-1-PE

100 μg PE conjugated

$670
A01231-1-carrier-free

Carrier Free

$370

More conjugates/formats

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A01231-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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