Product Info Summary
SKU: | A03379 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC |
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Product info
Product Name
Anti-Siah-2 (E266) Antibody
SKU/Catalog Number
A03379
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Siah-2 (E266) Antibody catalog # A03379. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Siah-2 (E266) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03379)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human SFTPD protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03379 is reactive to SIAH2 in Human, Mouse, Rat
Applications
A03379 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
34.615kDa
Background of SIAH2
Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments.
Ruiz A., J. Biol. Chem. 274:3834-3841(1999).
Mondal M.S., Biochemistry 39:5215-5220(2000).
Thompson D.A., Nat. Genet. 28:123-124(2001).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of SIAH2 using Anti-Siah-2 (E266) Antibody (A03379).
Immunohistochemistry (IHC) analyzes of Siah-2 (E266) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.For more protocol information of IHC
Protein Target Info & Infographic
Gene/Protein Information For SIAH2 (Source: Uniprot.org, NCBI)
Gene Name
SIAH2
Full Name
E3 ubiquitin-protein ligase SIAH2
Weight
34.615kDa
Superfamily
SINA (Seven in absentia) family
Alternative Names
E3 ubiquitin-protein ligase SIAH2; EC 6.3.2; EC 6.3.2.-; hSiah2; seven in absentia (Drosophila) homolog 2; seven in absentia homolog 2 (Drosophila); Seven in absentia homolog 2; siah-2 SIAH2 hSiah2 siah E3 ubiquitin protein ligase 2 E3 ubiquitin-protein ligase SIAH2|RING-type E3 ubiquitin transferase SIAH2|seven in absentia homolog 2|siah-2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SIAH2, check out the SIAH2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SIAH2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Siah-2 (E266) Antibody (A03379)
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No publications found for A03379
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Customer Reviews
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