Anti-SIPA1L3 Antibody

Product Name

Anti-SIPA1L3 Antibody

View all SIPA1L3 Antibodies

SKU/Catalog Number

A10403

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-SIPA1L3 Antibody (Catalog # A10403). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

SIPA1L3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-SIPA1L3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10403)

Host

Rabbit

Contents

SIPA1L3 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

SIPA1L3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human SIPA1L3. The immunogen is located within amino acids 80 - 130 of SIPA1L3.

Reactive Species

A10403 is reactive to SIPA1L3 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

194.6 kDa

Background of SIPA1L3

Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A10403 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

SIPA1L3 antibody can be used for detection of SIPA1L3 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information SIPA1L3

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