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- Table of Contents
SKI antibody (A01062) performs well in ELISA, IF, WB and shows reactivity with Human.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
- Over 1 Publication
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Immunofluorescence of Ski in human kidney tissue with Ski antibody at 20 μg/mL.
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Anti-Ski oncogene Ski Antibody
SKI antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human | Rabbit | ELISA, IF, WB |
Recommend Dilution
Application
Dilution
Species
SkiP antibody can be used for detection of Ski by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-Ski oncogene Ski Antibody
View all SKI Antibodies
View all SKI Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
Ski antibody can be stored at 4°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Host
Rabbit
Contents
Ski Antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Ski antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human Ski. The immunogen is located within the first 50 amino acids of Ski.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
80.0 kDa
Background of SKI
TGF-beta is a ubiquitously expressed cytokine that signals through the Smad protein family to regulate numerous cellular processes such as embryonic development and tumorigenesis. This signaling is negatively regulated by Ski, the mammalian homolog of the transforming protein of an avian retrovirus that induces oncogenic transformation of chicken embryo cells, and the related protein SnoN. Ski functions by binding to the Smad proteins and preventing their phosphorylation, thereby inhibiting their ability to bind DNA and activate the transcription of downstream genes. Ski will also bind to the Smad proteins specific to bone morphogenic proteins (BMPs) and block BMP signaling in mammalian cells.
Cite This Product
Anti-Ski oncogene Ski Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01062)
Publications
Application:
Species:
Zhang H,Wang JS,Chen XG,Kang L,Lin MB.Overexpression of c-Ski promotes cell proliferation, invasion and migration of gastric cancer associated fibroblasts.Kaohsiung J Med Sci.2019 Apr;35(4):214-221.doi:10.1002/kjm2.12042.Epub 2019 Mar 21.PMID:30896889.
Species: Human
PMID: 30896889
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Product Promise
We promise Anti-Ski oncogene Ski Antibody performs excellently in relevant applications for ELISA, IF, WB. If it doesn't perform as promised, we will refund the product. Learn more
In stock
Order Product
A01062
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
Troubleshooting
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Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 3, 2026