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Product Info Summary
| SKU: | A03281 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-SLAMF2 CD48 Antibody
View all CD48/SLAMF2 Antibodies
SKU/Catalog Number
A03281
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SLAMF2 CD48 Antibody (Catalog # A03281). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
SLAMF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-SLAMF2 CD48 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03281)
Host
Rabbit
Contents
SLAMF2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
SLAMF2 antibody was raised against a 19 amino acid synthetic peptide near the center of human SLAMF2. The immunogen is located within amino acids 90 - 140 of SLAMF2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Two isoforms of SLAMF2 are known to exist; this antibody will recognize both isoforms. SLAMF2 antibody is predicted to not cross-react with other SLAM protein family members.
Reactive Species
A03281 is reactive to CD48 in Human, Mouse, Rat
Applications
A03281 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
27.683kDa
Background of CD48/SLAMF2
The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SLAMF2 antibody can be used for detection of SLAMF2 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SLAMF2 in rat lung tissue lysate with SLAMF2 antibody at (A) 1 and (B) 2 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CD48 (Source: Uniprot.org, NCBI)
Gene Name
CD48
Full Name
CD48 antigen
Weight
27.683kDa
Alternative Names
BCM1 surface antigen; BCM1; BCM1Leukocyte antigen MEM-102; BLAST; BLAST1; BLAST1TCT.1; B-lymphocyte activation marker BLAST-1; CD48 antigen (B-cell membrane protein); CD48 antigen; CD48 molecule; CD48; hCD48; mCD48; MEM-102; SLAMF2 CD48 BCM1, BLAST, BLAST1, MEM-102, SLAMF2, hCD48, mCD48 CD48 molecule CD48 antigen|B-lymphocyte activation marker BLAST-1|BCM1 surface antigen|CD48 antigen (B-cell membrane protein)|SLAM family member 2|TCT.1|leukocyte antigen MEM-102|signaling lymphocytic activation molecule 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CD48, check out the CD48 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CD48: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SLAMF2 CD48 Antibody (A03281)
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No publications found for A03281
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