Anti-STAU1 Antibody

Product Name

Anti-STAU1 Antibody

View all Staufen Antibodies

SKU/Catalog Number

A04259

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-STAU1 Antibody (Catalog # A04259). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

STAU1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-STAU1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04259)

Host

Rabbit

Contents

STAU1 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

Clone: SK7

Isotype

IgG

Immunogen

STAU1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human STAU1. The immunogen is located within the last 50 amino acids of STAU1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

TSPY1L antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist; this antibody will detect only TSPY1L.

Reactive Species

A04259 is reactive to STAU1 in Human, Mouse, Rat

Applications

A04259 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

63.182kDa

Background of Staufen

STAU1 is a member of a family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human STAU1 also contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. STAU1 has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER. STAU1 is also known to interact with influenza ribonucleoproteins NS1, NP, and PA and is required for efficient viral replication.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

STAU1 antibody can be used for detection of STAU1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

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Western blot analysis of STAU1 in rat brain tissue lysate with STAU1 antibody at (A) 1 and (B) 2 μg/mL.

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Immunohistochemistry of STAU1 in human brain tissue with STAU1 antibody at 10 μg/mL.

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Immunofluorescence of STAU1 in Human Brain cells with STAU1 antibody at 20 μg/mL.

Gene/Protein Information For STAU1 (Source: Uniprot.org, NCBI)

Alternative Names

double-stranded RNA-binding protein Staufen homolog 1; FLJ25010; RNA binding protein (Drosophila); RNA-binding protein); staufen, RNA binding protein, homolog 1 (Drosophila) STAU1 PPP1R150, STAU staufen double-stranded RNA binding protein 1 double-stranded RNA-binding protein Staufen homolog 1|protein phosphatase 1, regulatory subunit 150|staufen, RNA binding protein, homolog 1

For more info on STAU1, check out the STAU1 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for STAU1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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