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Product Info Summary
| SKU: | A13447 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, ICC, WB |
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Product info
Product Name
Anti-SUSD3 Antibody
SKU/Catalog Number
A13447
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SUSD3 Antibody (Catalog # A13447). Tested in ELISA, WB, ICC applications. This antibody reacts with Human, Mouse.
Storage & Handling
SUSD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-SUSD3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13447)
Host
Rabbit
Contents
SUSD3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SUSD3 antibody was raised against a 16 amino acid peptide from near the center of human SUSD3. The immunogen is located within amino acids 120 - 170 of SUSD3.
Cross-reactivity
SUSD3 antibody is human and mouse reactive. Multiple isoforms of SUSD3 are known to exist.
Reactive Species
A13447 is reactive to SUSD3 in Human, Mouse
Observed Molecular Weight
68 kDa
Calculated molecular weight
27.1 kDa
Background of SUSD3
Little is known of the function of the sushi domain containing 3 protein (SUSD3), but its expression has been reported in estrogen receptor-alpha (ERalpha)-positive breast tumors with decreased expression reported in aggressive malignant tumors (1,2). Recently, SUSD3 has been found to promote estrogen-dependent cell proliferation and may regulate cell-cell and cell-substrate interactions and migration in breast cancer (3). Furthermore, elevated SUSD3 mRNA levels were observed in aromatase inhibitor-responsive breast tumors, suggesting that it may also serve as a novel predictor of response to endocrine therapy and a potential therapeutic target (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A13447 is guaranteed for ELISA, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SUSD3 antibody can be used for the detection of SUSD3 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SUSD3 in HeLa cell lysate with SUSD3 antibody at 1 μg/ml.
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Immunocytochemistry of SUSD3 in 3T3 cells with SUSD3 antibody at 5 μg/ml.
Specific Publications For Anti-SUSD3 Antibody (A13447)
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