SKU MA1091
Size 100μg/vial
Reactivity Human, Rat
Clonality Monoclonal
Clone Number SVP-38
Host Mouse
Ig Isotype Mouse IgG1
Applications IHC, WB

Overview

Product Name Anti-Synaptophysin Antibody (Monoclonal, SVP-38)
SKU/Catalog Number MA1091
Storage & Handling At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
Size 100μg/vial
Description Mouse IgG monoclonal antibody for Synaptophysin, synaptophysin (SYP) detection. Tested with WB, IHC-P, IHC-F in Human;Rat. No cross reactivity with other proteins.
Cite This Product Anti-Synaptophysin Antibody (Monoclonal, SVP-38) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1091)
Host Mouse
Immunogen Rat retina synaptosome.
Reactivity Human, Rat

Assay Details

Assay Dilutions Overview

Immunohistochemistry(Paraffin-embedded Section), 1-2μg/ml, Human, rat, By Heat
Immunohistochemistry(Frozen Section), 1-2μg/ml, Human, rat, -
Western blot, 0.5-1μg/ml, Human, rat

Boster's Secondary Antibodies And IHC, WB Kits

The following reagents are used to generate the images below.

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and IHC(F).

Images And Assay Conditions

/antibody/ma1091 1 WB anti synaptophysin antibody monoclonal svp 38.jpg

Anti-Synaptophysin antibody (monoclonal), MA1091, Western blotting
WB: Rat Brain Tissue Lysate

/antibody/ma1091 2 IHC anti synaptophysin antibody monoclonal svp 38.jpg

Anti-Synaptophysin antibody (monoclonal), MA1091, IHC(P)
IHC(P): Rat Brain Tissue

/antibody/ma1091 3 IHC anti synaptophysin antibody monoclonal svp 38.jpg

Anti-Synaptophysin antibody (monoclonal), MA1091, IHC(P)
IHC(P): Human Glioma Tissue

/antibody/ma1091 4 IHC anti synaptophysin antibody monoclonal svp 38.jpg

Anti-Synaptophysin antibody (monoclonal), MA1091, IHC(P)
IHC(P): Human meningeoma Tissue

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id P07825
Gene Name Syp
Protein Name Synaptophysin
Tissue Specificity Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
Alternative Names Synaptophysin;Major synaptic vesicle protein p38;Syp;
Subcellular Localization Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome.
Molecular Weight 33311 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.

Ontology

Protein Function Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity). .
Background Synaptophysin(SYP) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells. Ozcelik et al.(1990) concluded that the gene has 7 exons distributed over about 20 kb. SYP mapped the SYP locus to Xp11.23-p11.22. Regionalization of the gene on the X chromosome was also done with hamster/human hybrid cells in which various portions of the human X chromosome were present.

Order Product (MA1091)

Promotion:

Buy primary get secondary antibody for free.
Option Price
30ug sample size $99
100ug $280
100ug+Free HRP Secondary BA1050 $280
100ug+Free Biotin Secondary BA1001 $280

USD $280

Ships in 5-7 business days.

Troubleshooting

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Publications

Downregulation of caveolin-1 contributes to the synaptic plasticity deficit in the hippocampus of aged rats
Li Xh, Xin X, Wang Y, Wu Jz, Jin Zd, Ma Ln, Nie Cj, Xiao X, Hu Y, Jin Mw. J Alzheimers Dis. 2013;34(3):755-67. Doi: 10.3233/Jad-122017. Pentamethylquercetin Protects Against Diabetes-Related Cognitive Deficits In Diabetic Goto-Kakizaki Rats.
Liu Y, Liang Z, Liu J, Zou W, Li X, Wang Y, An L. Neural Regen Res. 2013 Oct 15;8(29):2725-33. Doi: 10.3969/J.Issn.1673-5374.2013.29.004. Downregulation Of Caveolin-1 Contributes To The Synaptic Plasticity Deficit In The Hippocampus Of Aged Rats.
Chen Y, Wei G, Nie H, Lin Y, Tian H, Liu Y, Yu X, Cheng S, Yan R, Wang Q, Liu Dh, Deng W, Lai Y, Zhou Jh, Zhang Sx, Lin Ww, Chen Df. Brain Res. 2014 Mar 13;1552:41-54. Doi: 10.1016/J.Brainres.2014.01.005. Epub 2014 Jan 20. ??-Asarone Prevents Autop...

Customer Q&As

Q: Is your western blot protocol provided from the website applicable for all your antibodies? Keyword: applications, WB
A: The protocol is applicable for all our antibodies in WB, the NC Membrane(0.45μm or 0.22μm) and transfer time(70 mins or 50 mins) depends on the protein molecular weight, details can be found in included protocol.
Q: Can I conjugate markers to this antibody? Can I link custom conjugates to this antibody? Keyword: conjugation
A: The antibody is stored with BSA and cannot be conjugated with markers. Carrier free antibodies are available upon request. Please contact support@bosterbio.com
Q: Can you provide monoclonal antibodies carrier free?
A: We cannot.
Q: What are some alternative names that could be used to describe this product?
A: Some common names include but are not limited to synaptophysin antibody, syp antibody