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- Table of Contents
Synaptophysin Antibodies
AND SYP ELISA kits, Synaptophysin Proteins
Many biological assays use antibodies to detect Synaptophysin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Synaptophysin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Synaptophysin antibodies...
Designing a Western blot for Synaptophysin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SYP Western Blot GuideSYP Infographic by Boster Bio
All SYP Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # A05049
100 μg/vial
Cat # A05049
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M05049
100 μl
Cat # M05049
100 μl
Mouse, Rat
WB
$370
Cat # M05049-3
100 μg/vial
Cat # M05049-3
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M05049-1
100 μl
Cat # M05049-1
100 μl
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A14531
0.1 mg
Cat # A14531
0.1 mg
Human, Mouse, Rat
ELISA
$480
Cat # EKC1555
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1555
1 kit, containing one 96-well plate and all necessary reagents
SYP Overview
Facts about Synaptophysin.
Synaptophysin (SYP)
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SYP |
| Uniprot: | P08247 |
| Entrez: | 6855 |
Family
| Belongs to: |
|---|
| synaptophysin/synaptobrevin family |
Alternative Names
Major synaptic vesicle protein p38; MRX; MRXSYP; Synaptophysin; SYP
Molecular Weight
Mass (kDA):
33.845 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xp11.23 |
| Sequence: | X; NC_000023.11 (49187815..49200193, complement) |
Tissue Specificity
Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
Subcellular Localizations
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome.
Diseases
- Neoplasms
- Alzheimer's Disease
- Carcinoma
- Brain Injuries
- Posttransfusion Purpura
- Malignant Neoplasms
- Nervousness
- Impaired Cognition
- Carcinoma, Neuroendocrine
- Tissue Adhesions
- Hyperplasia
- Janiceps
Pathways
- Localization
- Biofilm Formation
- Transport
- Aging
- Secretion
- Cell Proliferation
- Cell Adhesion
- Regeneration
- Exocytosis
- Pathogenesis
- Glucose Transport
- Synaptic Transmission
- Cell Growth
PTMs
- Phosphorylation
- Dephosphorylation
- Nitration
Research Areas
- Membrane Vesicle Markers
- Neuronal Cell Markers
- Neuroscience
- Neurotransmission
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SYP
bosterbio.com/bosterbio-gene-info-cards/SYP
References
PMID: 3120152 by Suedhof T.C., et al. The cDNA and derived amino acid sequences for rat and human synaptophysin.
PMID: 1975480 by Oezcelik T., et al. Synaptophysin: structure of the human gene and assignment to the X chromosome in man and mouse.
10 Publications of Boster Synaptophysin Antibodies & ELISA Kits
- PubMed ID: 10.1167/iovs.09-4504, Generation of Retinal Ganglion–like Cells from Reprogrammed Mouse Fibroblasts
- PubMed ID: 10.1080/00207454.2017.1387115, Effects of spontaneous recurrent seizures on cognitive function via modulation o...
- PubMed ID: 10.1016/j.tox.2017.04.001, The induction of cytochrome P450 2E1 by ethanol leads to the loss of synaptic pr...
- PubMed ID: 10.1016/j.neulet.2008.02.058, RETRACTED: Effect of ephedrine on neuronal plasticity of hypoxic-ischemic brain ...
- PubMed ID: 10.1016/j.brainres.2006.09.058, Catalpol increases hippocampal neuroplasticity and up-regulates PKC and BDNF in ...
- PubMed ID: 10.1002/syn.20684, Abnormality of synaptic vesicular associated proteins in cerebral cortex and hip...
- PubMed ID: 33531914, Lin J,Hao C,Gong Y,Zhang Y,Li Y,Feng Z,Xu X,Huang H,Liao W. Effect of Tetramethy...
- PubMed ID: 23271319, Li Xh, Xin X, Wang Y, Wu Jz, Jin Zd, Ma Ln, Nie Cj, Xiao X, Hu Y, Jin Mw. J Alzh...
- PubMed ID: 25206583, Liu Y, Liang Z, Liu J, Zou W, Li X, Wang Y, An L. Neural Regen Res. 2013 Oct 15;...
- PubMed ID: 24457043, Chen Y, Wei G, Nie H, Lin Y, Tian H, Liu Y, Yu X, Cheng S, Yan R, Wang Q, Liu Dh...
*More publications can be found for each product on its corresponding product page