Anti-Synaptotagmin-like protein 5 SYTL5 Antibody

Product Name

Anti-Synaptotagmin-like protein 5 SYTL5 Antibody

View all SYTL5 Antibodies

SKU/Catalog Number

A12927

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Synaptotagmin-like protein 5 SYTL5 Antibody (Catalog # A12927). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

SYTL5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Synaptotagmin-like protein 5 SYTL5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12927)

Host

Rabbit

Contents

SYTL5 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

SYTL5 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human SYTL5. The immunogen is located within amino acids 30 - 80 of SYTL5.

Cross-reactivity

Multiple isoforms of SYTL5 are known to exist. SYTL5 antibody is predicted to not cross-react with other SYTL protein family members.

Reactive Species

A12927 is reactive to SYTL5 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

81.5 kDa

Background of SYTL5

SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A12927 is guaranteed for ELISA, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

SYTL5 antibody can be used for detection of SYTL5 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information SYTL5

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