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Product Info Summary
| SKU: | A00991 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-Syndecan 1 SDC1 Antibody
View all Syndecan-1/CD138 Antibodies
SKU/Catalog Number
A00991
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Syndecan 1 SDC1 Antibody catalog # A00991. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Syndecan 1 SDC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00991)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human LRP6 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00991 is reactive to SDC1 in Human, Mouse, Rat
Applications
A00991 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
32.462kDa
Background of Syndecan-1/CD138
4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Gingras AC, et al. (1998) Genes Dev 12(4): 502-513.
Brugarolas J, et al. (2004) Genes Dev 18(23): 2893-2904.
Kumar V, et al. (2000) EMBO J 19(5): 1087-1097.
Moody CA, et al. (2005) J Virol 79(9): 5499-5506.
Burnett PE, et al. (1998) Proc Natl Acad Sci U S A 95(4): 1432-1437.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:2000-1:5000
IHC: 1:50-1:200
Validation Images & Assay Conditions
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Figure 2. Immunocytochemistry staining of SDC1 using Anti-Syndecan 1 SDC1 Antibody (A00991).
ICC staining Syndecan 1 in A431 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde
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Figure 1. Western blotting validation for Anti-Syndecan 1 SDC1 Antibody A00991
Western blot analysis of Syndecan 1 on NIH-3T3 cells lysates using anti-Syndecan 1 antibody at 1/500 dilution.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For SDC1 (Source: Uniprot.org, NCBI)
Gene Name
SDC1
Full Name
Syndecan-1
Weight
32.462kDa
Superfamily
syndecan proteoglycan family
Alternative Names
CD138 antigen; CD138; SDC; SDC1; SYND1heparan sulfate proteoglycan fibroblast growth factor receptor; syndecan 1; syndecan proteoglycan 1; syndecan; Syndecan1; Syndecan-1 SDC1 CD138, SDC, SYND1, syndecan syndecan 1 syndecan-1|CD138 antigen|heparan sulfate proteoglycan fibroblast growth factor receptor|syndecan proteoglycan 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SDC1, check out the SDC1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SDC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Syndecan 1 SDC1 Antibody (A00991)
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No publications found for A00991
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