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- Table of Contents
TARDBP antibody (A01001) performs well in ELISA, IF, ICC, WB and shows reactivity with Human, Mouse, Rat.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
- Over 1 Publication
Filter:
Immunofluorescence of TDP43 in Hela cells with TDP43 antibody at 20 μg/mL.
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Anti-TDP43 TARDBP Antibody
TARDBP antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse, Rat | Rabbit | ELISA, IF, ICC, WB |
Recommend Dilution
Application
Dilution
Species
TDP43 antibody can be used for detection of TDP43 by Western blot at 0.5 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-TDP43 TARDBP Antibody
View all TARDBP Antibodies
View all TARDBP Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
TDP43 antibody can be stored at 4°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Host
Rabbit
Contents
TDP43 Antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TDP43 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human TDP43. The immunogen is located within amino acids 60 - 110 of TDP43.
Cross-Reactivity
At least two isoforms are known to exist for this protein; this TDP43 antibody will recognize both isoforms.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
44.7 kDa
Background of TARDBP
TDP43 was initially identified as a novel cellular protein that bound to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3'splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.
Cite This Product
Anti-TDP43 TARDBP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01001)
Publications
Application:
Species:
Zhang Y,Yang C,Yang S,Guo Z.MiRNA-27a decreases ultraviolet B irradiation-induced cell damage. J Cell Biochem. 2020 Feb;121(2):1032-1038.doi: 10.1002/jcb.29337.Epub 2019 Aug 26.PMID: 31452277.
Species: Human
PMID: 31452277
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Product Promise
We promise Anti-TDP43 TARDBP Antibody performs excellently in relevant applications for ELISA, IF, ICC, WB. If it doesn't perform as promised, we will refund the product. Learn more
In stock
Order Product
A01001
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
Troubleshooting
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Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 14, 2026