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Product Info Summary
| SKU: | A08453 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Teashirt homolog 3 TSHZ3 Antibody
SKU/Catalog Number
A08453
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Teashirt homolog 3 TSHZ3 Antibody (Catalog # A08453). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
TSHZ3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Teashirt homolog 3 TSHZ3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08453)
Host
Rabbit
Contents
TSHZ3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
TSHZ3 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human TSHZ3. The immunogen is located within amino acids 60 - 110 of TSHZ3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms of CCDC22 are known to exist; this antibody will detect the two largest isoforms.
Reactive Species
A08453 is reactive to TSHZ3 in Human, Mouse, Rat
Applications
A08453 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
118.566kDa
Background of ZNF537
The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Both TSHZ3 and TSHZ1 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4. Recent experiments have also suggested this family of proteins may be involved in carcinogenesis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TSHZ3 antibody can be used for detection of TSHZ3 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 2.5 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TSHZ3 in mouse brain tissue lysate with TSHZ3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of TSHZ3 in mouse brain tissue with TSHZ3 antibody at 2.5 μg/mL.
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Immunofluorescence of TSHZ3 in mouse brain tissue with TSHZ3 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TSHZ3 (Source: Uniprot.org, NCBI)
Gene Name
TSHZ3
Full Name
Teashirt homolog 3
Weight
118.566kDa
Superfamily
teashirt C2H2-type zinc-finger protein family
Alternative Names
FLJ54422; KIAA1474; teashirt 3; teashirt zinc finger homeobox 3; zinc finger protein 537; ZNF537 TSHZ3 TSH3, ZNF537 teashirt zinc finger homeobox 3 teashirt homolog 3|teashirt family zinc finger 3|zinc finger protein 537
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TSHZ3, check out the TSHZ3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TSHZ3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Teashirt homolog 3 TSHZ3 Antibody (A08453)
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No publications found for A08453
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