Anti-Estrogen Inducible Protein pS2/Tff1 Antibody Picoband™

TFF1/pS2 antibody

Boster Bio Anti-Estrogen Inducible Protein pS2/Tff1 Antibody Picoband™ catalog # A01391. Tested in IHC, WB applications. This antibody reacts with Mouse.

Product Info Summary

SKU: A01391
Size: 100 μg/vial
Reactive Species: Mouse
Host: Rabbit
Application: IHC, WB

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Product Name

Anti-Estrogen Inducible Protein pS2/Tff1 Antibody Picoband™

View all TFF1/pS2 Antibodies

SKU/Catalog Number

A01391

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Estrogen Inducible Protein pS2/Tff1 Antibody Picoband™ catalog # A01391. Tested in IHC, WB applications. This antibody reacts with Mouse.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Estrogen Inducible Protein pS2/Tff1 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01391)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived mouse Tff1 recombinant protein (Position: Q22-F87). Mouse Tff1 shares 67.2% and 83.6% amino acid (aa) sequence identity with human and rat Tff1, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01391 is reactive to Tff1 in Mouse

Applications

A01391 is guaranteed for IHC, WB Boster Guarantee

Background of TFF1/pS2

TFF1 (Trefoil factor 1), also known as pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera directed to the TFF1 C terminus. Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Mouse
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Mouse, By Heat

Validation Images & Assay Conditions

Gene/Protein Information For Tff1 (Source: Uniprot.org, NCBI)

Uniprot ID

Q08423

Gene ID

21784

Gene Name

Tff1

Full Name

Trefoil factor 1

Weight

9.67kDa

Alternative Names

BCEI; BCEIbreast cancer, estrogen-inducible sequence expressed in; Breast cancer estrogen-inducible protein; breast cancer estrogen-inducible sequence; D21S21; gastrointestinal trefoil protein pS2; hP1.A; HPS2; PNR-2; Polypeptide P1.A; Protein pS2; PS2; TFF1; trefoil factor 1; trefoil factor, BCE1, human pS2 induced by estrogen from human breast cancercell line M10HP1.A Tff1|Bce, Bcei, P, PS2|trefoil factor 1|trefoil factor 1|protein pS2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Tff1, check out the Tff1 Infographic

Tff1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Tff1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Total: $315

SKU:A01391

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A01391
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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$50 fee for conjugation. Antibody size is reduced to 50ug.

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