Anti-TGF beta 2/TGFB2 Antibody Picoband™

TGF-beta 2 antibody

Boster Bio Anti-TGF beta 2/TGFB2 Antibody Picoband™ catalog # A00892-1. Tested in IHC, WB applications. This antibody reacts with Human. Cited in 1 publication(s).

Product Info Summary

SKU: A00892-1
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: IHC, WB

Product Name

Anti-TGF beta 2/TGFB2 Antibody Picoband™

View all TGF-beta 2 Antibodies

SKU/Catalog Number

A00892-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-TGF beta 2/TGFB2 Antibody Picoband™ catalog # A00892-1. Tested in IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TGF beta 2/TGFB2 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00892-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human TGF beta 2, identical to the related mouse and rat sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A00892-1 is reactive to TGFB2 in Human

Applications

A00892-1 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

48 kDa

Calculated molecular weight

47.748kDa

Background of TGF-beta 2

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in this gene may be associated with Loeys-Dietz syndrome. This gene encodes multiple isoforms that may undergo similar proteolytic processing.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Innovating Scientists Reward

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml

Validation Images & Assay Conditions

Gene/Protein Information For TGFB2 (Source: Uniprot.org, NCBI)

Gene Name

TGFB2

Full Name

Transforming growth factor beta-2 proprotein

Weight

47.748kDa

Superfamily

TGF-beta family

Alternative Names

BSC-1 cell growth inhibitor; cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; MGC116892; polyergin; TGFB2; TGFbeta 2; TGF-beta 2; TGF-beta2; TGF-beta-2; transforming growth factor beta-2; transforming growth factor, beta 2 TGFB2 G-TSF, LDS4, TGF-beta2 transforming growth factor beta 2 transforming growth factor beta-2 proprotein|BSC-1 cell growth inhibitor|cetermin|glioblastoma-derived T-cell suppressor factor|polyergin|prepro-transforming growth factor beta-2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on TGFB2, check out the TGFB2 Infographic

TGFB2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TGFB2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A00892-1 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Li X, Liu L, Shen Y, Wang T, Chen L, Xu D, Wen F. Biochem Biophys Res Commun. 2014 Oct 27;454(4):512-517. Doi: 10.1016/J.Bbrc.2014.10.106. [Epub Ahead Of Print] Microrna-26A Modulates Transforming Growth Factor Beta-1-Induced Proliferation In Huma...

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5 Customer Q&As for Anti-TGF beta 2/TGFB2 Antibody Picoband™

Question

My colleagues were content with the WB result of your anti-TGF beta 2/TGFB2 antibody. However we have been able to see positive staining in thalamus transforming growth factor beta-2: secreted using this antibody. Is that expected? Could you tell me where is TGFB2 supposed to be expressed?

Verified Customer

Verified customer

Asked: 2017-09-20

Answer

From literature, thalamus does express TGFB2. Generally TGFB2 expresses in latency-associated peptide: secreted,, transforming growth factor beta-2: secreted. Regarding which tissues have TGFB2 expression, here are a few articles citing expression in various tissues:
Lung, Pubmed ID: 1764261
Thalamus, Pubmed ID: 14702039

Boster Scientific Support

Answered: 2017-09-20

Question

We are currently using anti-TGF beta 2/TGFB2 antibody A00892-1 for human tissue, and we are satisfied with the IHC-P results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on goat tissues as well?

Verified Customer

Verified customer

Asked: 2017-08-09

Answer

The anti-TGF beta 2/TGFB2 antibody (A00892-1) has not been tested for cross reactivity specifically with goat tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in goat you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2017-08-09

Question

We bought anti-TGF beta 2/TGFB2 antibody for WB on lung a few years ago. I am using human, and We intend to use the antibody for IHC-P next. you antibody examining lung as well as thalamus in our next experiment. Could you please give me some suggestion on which antibody would work the best for IHC-P?

G. Jackson

Verified customer

Asked: 2015-12-04

Answer

I have checked the website and datasheets of our anti-TGF beta 2/TGFB2 antibody and I see that A00892-1 has been tested on human in both WB and IHC-P. Thus A00892-1 should work for your application. Our Boster satisfaction guarantee will cover this product for IHC-P in human even if the specific tissue type has not been validated. We do have a comprehensive range of products for IHC-P detection and you can check out our website bosterbio.com to find out more information about them.

Boster Scientific Support

Answered: 2015-12-04

Question

We have seen staining in rat thalamus. Any tips? Is anti-TGF beta 2/TGFB2 antibody supposed to stain thalamus positively?

Z. Roberts

Verified customer

Asked: 2015-03-23

Answer

From literature thalamus does express TGFB2. From Uniprot.org, TGFB2 is expressed in lung, thalamus, among other tissues. Regarding which tissues have TGFB2 expression, here are a few articles citing expression in various tissues:
Lung, Pubmed ID: 1764261
Thalamus, Pubmed ID: 14702039

Boster Scientific Support

Answered: 2015-03-23

Question

Our lab want to know about using your anti-TGF beta 2/TGFB2 antibody for negative regulation of macrophage cytokine production studies. Has this antibody been tested with western blotting on hepg2 whole cell lysates? We would like to see some validation images before ordering.

G. Wu

Verified customer

Asked: 2013-11-08

Answer

Thanks for your inquiry. This A00892-1 anti-TGF beta 2/TGFB2 antibody is tested on human placenta tissue, hela whole cell lysates, hepg2 whole cell lysates, a549 whole cell lysates. It is guaranteed to work for IHC-P, WB in human, mouse, rat. Our Boster guarantee will cover your intended experiment even if the sample type has not been be directly tested.

Boster Scientific Support

Answered: 2013-11-08

Order DetailsPrice
A00892-1

100μg

$370
A00892-1-10ug

10μg sample (liquid)

$99
A00892-1-Biotin

100 μg Biotin conjugated

$570
A00892-1-Cy3

100 μg Cy3 conjugated

$570
A00892-1-Dylight488

100 μg Dylight488 conjugated

$570
A00892-1-Dylight550

100 μg Dylight550 conjugated

$570
A00892-1-Dylight594

100 μg Dylight594 conjugated

$570
A00892-1-FITC

100 μg FITC conjugated

$570
A00892-1-HRP

100 μg HRP conjugated

$570
A00892-1-APC

100 μg APC conjugated

$670
A00892-1-PE

100 μg PE conjugated

$670
A00892-1-carrier-free

Carrier Free

$370

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A00892-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
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$370.00

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