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- Table of Contents
TIGIT antibody (M01962-1) performs well in ELISA, Flow Cytometry, IF, IHC-P, ICC, WB and shows reactivity with Human.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
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Flow cytometry analysis of TIGIT over expressing HEK293 cells using TIGIT antibody at 1 μg/ml. Blue: untransfected HEK293 cells. Yellow: TIGIT over expressing HEK293 cells.
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Anti-TIGIT Monoclonal Antibody [4A10]
TIGIT antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human | Mouse | ELISA, Flow Cytometry, IF, IHC-P, ICC, WB |
Recommend Dilution
Application
Dilution
Species
TIGIT antibody can be used for immunohistochemistry starting at 2 μg/mL. For immunofluorescence start at 1 μg/mL. For flow cytometry at 1 μg/ml. For immunocytochemistry at 1 μg/mL. For Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples; Immunocytochemistry in human samples; Immunofluorescence in human samples and Flow Cytometry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-TIGIT Monoclonal Antibody [4A10]
View all TIGIT Antibodies
View all TIGIT Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
TIGIT antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Host
Mouse
Contents
TIGIT Antibody is supplied in PBS containing 0.02% sodium azide and 50% glycerol.
Clonality
Monoclonal
Clone Number
Clone: 4A10
Isotype
IgG1
Immunogen
TIGIT antibody was raised against the extracellular domain of human TIGIT
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
26.3 kDa
Background of TIGIT
The T cell immunoreceptor with Ig and ITIM domains (TIGIT) is a member of the PVR (poliovirus receptor) family of immunoglobin proteins. It is expressed on several classes of T cells including follicular B helper T cells (TFH). TIGIT has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses (1). Similar to other immune checkpoint proteins such as PD-1, TIGIT is upregulated on exhausted T cells in chronic viral infections and cancer. Blockade of both TIGIT and PD-1 pathways leads to tumor rejection in mice suggesting that it may be of therapeutic use against cancer (2).
Cite This Product
Anti-TIGIT Monoclonal Antibody [4A10] (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01962-1)
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Product Promise
We promise Anti-TIGIT Monoclonal Antibody [4A10] performs excellently in relevant applications for ELISA, Flow Cytometry, IF, IHC-P, ICC, WB. If it doesn't perform as promised, we will refund the product. Learn more
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M01962-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
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We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 6, 2026