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Product Info Summary
| SKU: | A04342 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-TLX1 Antibody
SKU/Catalog Number
A04342
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TLX1 Antibody (Catalog # A04342). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
TLX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-TLX1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04342)
Host
Rabbit
Contents
TLX1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TLX1 antibody was raised against a 16 amino acid peptide near the amino terminus of human TLX1. The immunogen is located within the first 50 amino acids of TLX1.
Cross-reactivity
Multiple isoforms of TLX1 exist due to alternative splicing events. TLX1 antibody is predicted to not cross-react with other TLX proteins.
Reactive Species
A04342 is reactive to TLX1 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
34.4 kDa
Background of TLX1
The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX1, also called homeobox11 (HOX11), as it is located outside of the four mammalian Hox clusters, is a DNA-binding nuclear transcription factor. TLX1 encodes a homeobox-domain containing protein and is containing a glycine and proline-rich amino terminus. TLX1 is required for maintenance of the developing spleen and cell survival. TLX1 is highly expressed in T-cell leukemia and lymphoid neoplasias as a result of translocation. TLX1-deficient mice have no spleen.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04342 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TLX1 antibody can be used for detection of TLX1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TLX1 in mouse spleen tissue lysate with TLX1 antibody at (A) 1 μg/mL and (B) 2 μg/mL.
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Immunohistochemistry of TLX1 in human spleen tissue with TLX1 antibody at 2.5 μg/ml.
Specific Publications For Anti-TLX1 Antibody (A04342)
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