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Product Info Summary
| SKU: | A04342 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-TLX1 Antibody
SKU/Catalog Number
A04342
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TLX1 Antibody (Catalog # A04342). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
TLX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-TLX1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04342)
Host
Rabbit
Contents
TLX1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
TLX1 antibody was raised against a 16 amino acid peptide near the amino terminus of human TLX1. The immunogen is located within the first 50 amino acids of TLX1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Multiple isoforms of TLX1 exist due to alternative splicing events. TLX1 antibody is predicted to not cross-react with other TLX proteins.
Reactive Species
A04342 is reactive to TLX1 in Human, Mouse, Rat
Applications
A04342 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
34.365kDa
Background of HOX11
The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX1, also called homeobox11 (HOX11), as it is located outside of the four mammalian Hox clusters, is a DNA-binding nuclear transcription factor. TLX1 encodes a homeobox-domain containing protein and is containing a glycine and proline-rich amino terminus. TLX1 is required for maintenance of the developing spleen and cell survival. TLX1 is highly expressed in T-cell leukemia and lymphoid neoplasias as a result of translocation. TLX1-deficient mice have no spleen.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TLX1 antibody can be used for detection of TLX1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TLX1 in mouse spleen tissue lysate with TLX1 antibody at (A) 1 μg/mL and (B) 2 μg/mL.
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Immunohistochemistry of TLX1 in human spleen tissue with TLX1 antibody at 2.5 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For TLX1 (Source: Uniprot.org, NCBI)
Gene Name
TLX1
Full Name
T-cell leukemia homeobox protein 1
Weight
34.365kDa
Alternative Names
homeo box 11 (T-cell lymphoma 3-associated breakpoint); homeo box-11 (T-cell leukemia-3 associated breakpoint, homologous to DrosophilaNotch); Homeobox protein Hox-11; HOX11T-cell leukemia, homeobox 1; Proto-oncogene TCL-3; T-cell leukemia homeobox 1; T-cell leukemia homeobox protein 1; T-cell leukemia/lymphoma protein 3; TCL3MGC163402 TLX1 HOX11, TCL3 T cell leukemia homeobox 1 T-cell leukemia homeobox protein 1|T-cell leukemia/lymphoma protein 3|homeo box-11 (T-cell leukemia-3 associated breakpoint, homologous to Drosophila Notch)|homeobox protein Hox-11|proto-oncogene TCL-3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TLX1, check out the TLX1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TLX1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TLX1 Antibody (A04342)
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No publications found for A04342
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Customer Reviews
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