Product Info Summary
SKU: | A06360 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-TMEM70 Antibody
SKU/Catalog Number
A06360
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TMEM70 Antibody (Catalog # A06360). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
TMEM70 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TMEM70 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06360)
Host
Rabbit
Contents
TMEM70 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
TMEM70 antibody was raised against a 14 amino acid synthetic peptide near the center of human TMEM70. The immunogen is located within amino acids 150 - 200 of TMEM70.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
INPP4B antibody is human, mouse and rat reactive. At least two isoforms of INPP4B are known to exist; this antibody only detects the longer isoform. INPP4B antibody is predicted to not cross-react with INPP4A.
Reactive Species
A06360 is reactive to TMEM70 in Human, Mouse, Rat
Applications
A06360 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
28.969kDa
Background of TMEM70
TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TMEM70 antibody can be used for detection of TMEM70 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TMEM70 in human liver tissue lysate with TMEM70 antibody at 1 μg/mL.
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Immunohistochemistry of TMEM70 in rat liver tissue with TMEM70 antibody at 5 μg/mL.
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Immunofluorescence of TMEM70 in rat liver tissue with TMEM70 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TMEM70 (Source: Uniprot.org, NCBI)
Gene Name
TMEM70
Full Name
Transmembrane protein 70, mitochondrial
Weight
28.969kDa
Superfamily
TMEM70 family
Alternative Names
FLJ20533; transmembrane protein 70; transmembrane protein 70, mitochondrial TMEM70 MC5DN2 transmembrane protein 70 transmembrane protein 70, mitochondrial
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TMEM70, check out the TMEM70 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TMEM70: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TMEM70 Antibody (A06360)
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No publications found for A06360
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Customer Reviews
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