Anti-TNF beta/LTA Antibody

LTA antibody

Boster Bio Anti-TNF beta/LTA Antibody catalog # PA1361-1. Tested in WB applications. This antibody reacts with Human.

Product Info Summary

SKU: PA1361-1
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: WB

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Product Name

Anti-TNF beta/LTA Antibody

View all LTA Antibodies

SKU/Catalog Number

PA1361-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-TNF beta/LTA Antibody catalog # PA1361-1. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TNF beta/LTA Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1361-1)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human TNF beta (45-59aa AQTARQHPKMHLAHS).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

PA1361-1 is reactive to LTA in Human

Applications

PA1361-1 is guaranteed for WB Boster Guarantee

Background of LTA

Lymphotoxin (previously known as tumor necrosis factor-beta) is a lymphokine cytokine.It is a protein that is produced by Th1 type T-cells and induces vascular endothelial cells to change their surface adhesion molecules to allow phagocytic cells to bind to them. Lymphotoxin is homologous to Tumor Necrosis Factor beta, but secreted by T-cells. It is paracrine due to the small amounts produced. The effects are similar to TNF-alpha, but TNF-beta is also important for the development of lymphoid organs. Nedwin et al. (1985) found that TNFA and TNFB are closely linked on chromosome 6. Study of hybrid cells made with rearranged human chromosome 6 showed that both TNFA and TNFB map to the 6p23-q12 segment.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For LTA (Source: Uniprot.org, NCBI)

Uniprot ID

P01374

Gene ID

4049

Gene Name

LTA

Full Name

Lymphotoxin-alpha

Weight

22.297kDa

Superfamily

tumor necrosis factor family

Alternative Names

LT; LTA; LT-alpha; lymphotoxin alpha (TNF superfamily, member 1); Lymphotoxin alpha; Lymphotoxinalpha; Lymphotoxin-alpha; tnfb; TNF-beta; TNFBlymphotoxin-alpha; TNFSF1; TNFSF1B; TNFSF1TNF-beta; tumor necrosis factor beta; Tumor necrosis factor ligand superfamily member 1 LTA LT, TNFB, TNFSF1, TNLG1E lymphotoxin alpha lymphotoxin-alpha|LT-alpha|TNF superfamily, member 1|TNF-beta|truncated lymphotoxin alpha|tumor necrosis factor beta|tumor necrosis factor ligand 1E|tumor necrosis factor ligand superfamily member 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on LTA, check out the LTA Infographic

LTA infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for LTA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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1 Customer Q&As for Anti-TNF beta/LTA Antibody

Question

We are currently using anti-TNF beta/LTA antibody PA1361-1 for human tissue, and we are well pleased with the WB results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on primate tissues as well?

J. Johnson

Verified customer

Asked: 2016-08-09

Answer

The anti-TNF beta/LTA antibody (PA1361-1) has not been tested for cross reactivity specifically with primate tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in primate you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2016-08-09

Size

Conjugation

Total: $315

SKU:PA1361-1

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PA1361-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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