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- Table of Contents
Lymphotoxin-alpha Antibodies
AND LTA ELISA kits, Lymphotoxin-alpha Proteins
Many biological assays use antibodies to detect Lymphotoxin-alpha, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lymphotoxin-alpha in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lymphotoxin-alpha antibodies...
Designing a Western blot for Lymphotoxin-alpha? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the LTA Western Blot GuideLTA Infographic by Boster Bio
All LTA Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0584
96 wells/kit, with removable strips.
Cat # EK0584
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A02399-1
100 µg/vial
Cat # A02399-1
100 µg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02399-3
100 μl/vial
Cat # M02399-3
100 μl/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, WB
$523
Cat # M02399
100 µl
Cat # M02399
100 µl
Dog, Human, Mouse, Rat
IP, IF, IHC, WB
$523
Cat # M02399-1
100 µl
Cat # M02399-1
100 µl
Dog, Human, Monkey, Mouse, Rat
IP, IHC, WB
$523
Cat # M02399-2
100 µl
Cat # M02399-2
100 µl
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00746-3
100 μg
Cat # M00746-3
100 μg
Human
$628
Cat # LS004048
20 µg, 100 µg
Cat # LS004048
20 µg, 100 µg
Mouse
Cell Culture
$77
Cat # PROTP09225
5ug,20ug,100ug
Cat # PROTP09225
5ug,20ug,100ug
Human
Cell Culture
$77
Cat # PROTP01374-6
5ug,20ug,100ug
Cat # PROTP01374-6
5ug,20ug,100ug
SDS-PAGE
$250
Cat # PROTP09960
Starting from 4ug
Cat # PROTP09960
Starting from 4ug
LTA Overview
Facts about Lymphotoxin-alpha.
Lymphotoxin-alpha (LTA)
Cytokine that in its own homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR.
Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. .
Gene Information
| Human | |
|---|---|
| Gene Name: | LTA |
| Uniprot: | P01374 |
| Entrez: | 4049 |
Family
| Belongs to: |
|---|
| tumor necrosis factor family |
Alternative Names
LT; LTA; LT-alpha; lymphotoxin alpha (TNF superfamily, member 1); Lymphotoxin alpha; Lymphotoxinalpha; Lymphotoxin-alpha; tnfb; TNF-beta; TNFBlymphotoxin-alpha; TNFSF1; TNFSF1B; TNFSF1TNF-beta; tumor necrosis factor beta; Tumor necrosis factor ligand superfamily member 1
Molecular Weight
Mass (kDA):
22.297 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p21.33 |
| Sequence: | 6; NC_000006.12 (31560550..31574324) |
Subcellular Localizations
Secreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated.
Diseases
- Inflammation
- Infective Disorder
- Malignant Neoplasms
- Inflammatory Response
- Systemic Infection
- Tissue Adhesions
- Myocardial Infarction
- Pneumonia
- Infarction
- Neoplasms
- Bacterial Infections
- Coronary Artery Disease
- Asthma
Pathways
- Secretion
- Pathogenesis
- Immune Response
- Platelet Aggregation
- Inflammatory Response
- Cytokine Production
- Virulence
- Localization
- Innate Immune Response
- Glycosylation
- Coagulation
- Autolysis
- Transport
PTMs
- Phosphorylation
- Glycosylation
- Cleavage
- Oxidation
- Acylation
- Ribosylation
- Acetylation
- Reduction
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LTA
bosterbio.com/bosterbio-gene-info-cards/LTA
References
PMID: 3555974 by Nedospasov S.A., et al. Tandem arrangement of genes coding for tumor necrosis factor (TNF- alpha) and lymphotoxin (TNF-beta) in the human genome.
PMID: 3001109 by Nedwin G.E., et al. Structure and chromosomal localization of the human lymphotoxin gene.
4 Publications of Boster Lymphotoxin-alpha Antibodies & ELISA Kits
- PubMed ID: 10.1038/s41598-020-57927-6, Associations of lymphotoxin-a ( LTA ) rs909253 A/G gene polymorphism, plasma lev...
- PubMed ID: 22505802, Effects of Reactive Nitrogen Scavengers on NK-Cell-Mediated Killing of K562 Cell...
- PubMed ID: 26117660, Wang M, Zheng Z, Meng J, Wang H, He M, Zhang F, Liu Y, Hu B, He Z, Hu Q, Wang H....
- PubMed ID: 25725585, Tang D, Gao J, Wang S, Yuan Z, Ye N, Chong Y, Xu C, Jiang X, Li B, Yin W, Miao Y...
*More publications can be found for each product on its corresponding product page