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- Table of Contents
Lymphotoxin-alpha Antibodies
AND LTA ELISA kits, Lymphotoxin-alpha Proteins
Many biological assays use antibodies to detect Lymphotoxin-alpha, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lymphotoxin-alpha in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lymphotoxin-alpha antibodies...
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LTA Infographic by Boster Bio
All LTA Products
Product
Figures
Specificity
Applications
Price
Human TNF Beta/Lymphotoxin-alpha ELISA Kit PicoKine®
2 Citations 7 Q&As
Human
ELISA
$499
Cat # EK0584
96 wells/kit, with removable strips.
Cat # EK0584
96 wells/kit, with removable strips.
Human
Cell Culture
$77
Cat # PROTP01374-6
5ug,20ug,100ug
Cat # PROTP01374-6
5ug,20ug,100ug
Mouse
Cell Culture
$77
Cat # PROTP09225
5ug,20ug,100ug
Cat # PROTP09225
5ug,20ug,100ug
Mouse TNF beta ELISA Kit PicoKine®
1 Citations
Mouse
ELISA
$499
Cat # EK0585
96 wells/kit, with removable strips.
Cat # EK0585
96 wells/kit, with removable strips.
Cynomolgus monkey, Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00746-3
100 μg
Cat # M00746-3
100 μg
LTA Overview
Facts about Lymphotoxin-alpha.
Lymphotoxin-alpha (LTA)
Cytokine that in its own homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR.
Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. .
Gene Information
| Human | |
|---|---|
| Gene Name: | LTA |
| Uniprot: | P01374 |
| Entrez: | 4049 |
Family
| Belongs to: |
|---|
| tumor necrosis factor family |
Alternative Names
LT; LTA; LT-alpha; lymphotoxin alpha (TNF superfamily, member 1); Lymphotoxin alpha; Lymphotoxinalpha; Lymphotoxin-alpha; tnfb; TNF-beta; TNFBlymphotoxin-alpha; TNFSF1; TNFSF1B; TNFSF1TNF-beta; tumor necrosis factor beta; Tumor necrosis factor ligand superfamily member 1
Molecular Weight
Mass (kDA):
22.297 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p21.33 |
| Sequence: | 6; NC_000006.12 (31560550..31574324) |
Subcellular Localizations
Secreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated.
Diseases
- Inflammation
- Infective Disorder
- Malignant Neoplasms
- Inflammatory Response
- Systemic Infection
- Tissue Adhesions
- Myocardial Infarction
- Pneumonia
- Infarction
- Neoplasms
- Bacterial Infections
- Coronary Artery Disease
- Asthma
Pathways
- Secretion
- Pathogenesis
- Immune Response
- Platelet Aggregation
- Inflammatory Response
- Cytokine Production
- Virulence
- Localization
- Innate Immune Response
- Glycosylation
- Coagulation
- Autolysis
- Transport
PTMs
- Phosphorylation
- Glycosylation
- Cleavage
- Oxidation
- Acylation
- Ribosylation
- Acetylation
- Reduction
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LTA
bosterbio.com/bosterbio-gene-info-cards/LTA
References
PMID: 3555974 by Nedospasov S.A., et al. Tandem arrangement of genes coding for tumor necrosis factor (TNF- alpha) and lymphotoxin (TNF-beta) in the human genome.
PMID: 3001109 by Nedwin G.E., et al. Structure and chromosomal localization of the human lymphotoxin gene.
4 Publications of Boster Lymphotoxin-alpha Antibodies & ELISA Kits
- PubMed ID: 10.1038/s41598-020-57927-6, Associations of lymphotoxin-a ( LTA ) rs909253 A/G gene polymorphism, plasma lev...
- PubMed ID: 22505802, Effects of Reactive Nitrogen Scavengers on NK-Cell-Mediated Killing of K562 Cell...
- PubMed ID: 26117660, Wang M, Zheng Z, Meng J, Wang H, He M, Zhang F, Liu Y, Hu B, He Z, Hu Q, Wang H....
- PubMed ID: 25725585, Tang D, Gao J, Wang S, Yuan Z, Ye N, Chong Y, Xu C, Jiang X, Li B, Yin W, Miao Y...
*More publications can be found for each product on its corresponding product page