Anti-Toll-like receptor 11 TLR11 Antibody

Product Name

Anti-Toll-like receptor 11 TLR11 Antibody

View all TLR11 Antibodies

SKU/Catalog Number

A33174

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Toll-like receptor 11 TLR11 Antibody (Catalog # A33174). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Mouse.

Storage & Handling

TLR11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Toll-like receptor 11 TLR11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A33174)

Host

Rabbit

Contents

TLR11 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

TLR11 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of mouse TLR11. The immunogen is located within the last 50 amino acids of TLR11.

Reactive Species

A33174 is reactive to TLR11 in Mouse

Observed Molecular Weight

68 kDa

Calculated molecular weight

105.9 kDa

Background of TLR11

Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A33174 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

TLR11 antibody can be used for detection of TLR11 by Western blot at 0.5 to 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2 μg/mL. For immunofluorescence start at 10 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information TLR11

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