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- Table of Contents
TRIM21 antibody (A02079) performs well in ELISA, IF, IHC-P, WB and shows reactivity with Human.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
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Immunofluorescence Validation of TRIM21 in Human Small Intestine Tissue
Immunofluorescent analysis of 4% paraformaldehyde-fixed human small intestine tissue labeling TRIM21 with A02079 at 20 μg/mL, followed by goat anti-rabbit IgG secondary antibody at 1/500 dilution (red).
Immunofluorescent analysis of 4% paraformaldehyde-fixed human small intestine tissue labeling TRIM21 with A02079 at 20 μg/mL, followed by goat anti-rabbit IgG secondary antibody at 1/500 dilution (red).
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Anti-TRIM21 Antibody
TRIM21 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human | Rabbit | ELISA, IF, IHC-P, WB |
Recommend Dilution
Application
Dilution
Species
WB: 0.5-2 μg/mL; IHC: 5 μg/mL; IF: 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples; Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-TRIM21 Antibody
View all TRIM21 Antibodies
View all TRIM21 Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
TRIM21 antibody can be stored at 4°C, stable for up to one year.
Host
Rabbit
Contents
TRIM21 Antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Anti-TRIM21 antibody was raised against a peptide corresponding to 16 amino acids near the center of human TRIM21. The immunogen is located within amino acids 290-340 of TRIM21.
Cross-Reactivity
TRIM21 antibody is human specific. This antibody is predicted to not cross-react with TRIM6.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
54.2 kDa
Background of TRIM21
TRIM21, a member of the tripartite motif (TRIM) family, is a part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus (1). RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus (2). TRIM21 also acts as a cytosolic antibody receptor; detection of intracellular antibodies activate immune signaling by stimulating the transcription factor pathways of NF-kappaB, AP-1, IRF3, IRF5, and IRF7, resulting in the production of proinflammatory cytokines and the induction of an antiviral state (3).
Cite This Product
Anti-TRIM21 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02079)
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Product Promise
We promise Anti-TRIM21 Antibody performs excellently in relevant applications for ELISA, IF, IHC-P, WB. If it doesn't perform as promised, we will refund the product. Learn more
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A02079
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
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We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 13, 2026