Anti-TSLP Receptor Crlf2 Antibody

Product Name

Anti-TSLP Receptor Crlf2 Antibody

View all CRLF2 Antibodies

SKU/Catalog Number

A04167

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-TSLP Receptor Crlf2 Antibody (Catalog # A04167). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.

Storage & Handling

TSLP Receptor antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-TSLP Receptor Crlf2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04167)

Host

Rabbit

Contents

TSLP Receptor Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

TSLP Receptor antibody was raised against a 19 amino acid synthetic peptide from near the center of human TSLP receptor. The immunogen is located within amino acids 140 - 190 of TSLP Receptor.

Cross-reactivity

At least two isoforms of TSLP-R are known to exist; this antibody will recognize both isoforms.

Reactive Species

A04167 is reactive to CRLF2 in Human

Observed Molecular Weight

68 kDa

Calculated molecular weight

37.8 kDa

Background of CRLF2

Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells; co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A04167 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

TSLP-R antibody can be used for detection of TSLP-R by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information CRLF2

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